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Chemical Structure| 19867-34-6 Chemical Structure| 19867-34-6

Structure of 19867-34-6

Chemical Structure| 19867-34-6

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Product Details of [ 19867-34-6 ]

CAS No. :19867-34-6
Formula : C13H17NO
M.W : 203.28
SMILES Code : N(CC1)(CC2=CC=CC=C2)CCC31CO3
MDL No. :MFCD06808592
InChI Key :KJKHFQBTYMJFNP-UHFFFAOYSA-N
Pubchem ID :89238

Safety of [ 19867-34-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 19867-34-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 19867-34-6 ]

[ 19867-34-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 19867-34-6 ]
  • [ 926-39-6 ]
  • (2-[(1-benzyl-4-hydroxypiperidin-4-yl)methyl]amino}ethoxy)sulfonic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
71.5 g With triethylamine; In methanol; water; at 50℃; for 36h; To a stirred solution of 6-benzyl-1-oxa-6-azaspiro[2.5]octane (from step a, 50.7 g) in MeOH (350mL)/H20 (64 mL), at RT, 2-aminoethylhydrogensulfate (60 g, 422.8 mmol), was added followed by TEA (58.8 mL, 422.8 mmol) and the solution was stirred at 50 °C for 36 hrs. The day after, solid was filteredoff and solvent was eliminated under reduced pressure. The residue was triturated with DCM/MeOH(95:5) affording (2-[(1-benzyl-4-hydroxypiperidin-4-yl)methyl]amino}ethoxy)sulfonic acid as white solid(71.5 g). Presence of desired product and 2-aminoethylhydrogensulfate.
 

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