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Chemical Structure| 202591-85-3 Chemical Structure| 202591-85-3

Structure of 202591-85-3

Chemical Structure| 202591-85-3

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Product Details of [ 202591-85-3 ]

CAS No. :202591-85-3
Formula : C5H5ClO2
M.W : 132.55
SMILES Code : O=C(Cl)OCC#CC
MDL No. :MFCD00274353

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Application In Synthesis of [ 202591-85-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 202591-85-3 ]

[ 202591-85-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 7311-95-7 ]
  • [ 202591-85-3 ]
  • 2-(but-2-ynyloxycarbonylamino)-benzo[b]thiophene-3-carboxylic acid ethyl ester [ No CAS ]
YieldReaction ConditionsOperation in experiment
8% In 1,4-dioxane; at 20℃; for 65.0h; To a stirred solution of aminothiophene UO (lOOmg, 0.45 mmol) in 1,4-dioxane (10ml) was added 2-butynyl chlorofonnate (60p1, 0.5 mmol). The reaction mixture was stirred at room temperature for 65 hours and then evaporated to dryness under reduced pressure to give a brown solid (114mg). Chromatography of the crude product, using 25% ether in hexane (by volume) as eluant, gave the desired product as an off-white solid (1 1mg, 8%). lH NMR 5H (400MHz, CDC13) : 11.10 (1H, br s), 8.25 (1H, d), 7.70 (1H, d), 7.40 (1H, t), 7. 30 (1H, t), 4.85 (2H, m) 4.45 (2H, q), 1.90 (3H, m) and 1.50 (3H, t) ppm.
 

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