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Chemical Structure| 206360-56-7 Chemical Structure| 206360-56-7

Structure of 206360-56-7

Chemical Structure| 206360-56-7

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Product Details of [ 206360-56-7 ]

CAS No. :206360-56-7
Formula : C8H5F2NO4
M.W : 217.13
SMILES Code : OC(=O)C(F)(F)C1=CC=C(C=C1)[N+]([O-])=O
MDL No. :MFCD11504878
Boiling Point : No data available
InChI Key :RZESONLWCQFNHX-UHFFFAOYSA-N
Pubchem ID :46739201

Safety of [ 206360-56-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 206360-56-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 206360-56-7 ]

[ 206360-56-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 206360-56-7 ]
  • [ 29848-57-5 ]
YieldReaction ConditionsOperation in experiment
79% With potassium fluoride; In N,N-dimethyl-formamide; at 170℃; for 12h;Inert atmosphere; Accordance with the above scheme, the 2-neck tube 2,2-difluoro-2-(4-nitrophenyl)acetic acid (Compound 4b; 65.1 mg, 0.3 mmol), potassium fluoride (87.2 mg, 1.5 mmol), DMF (1.2 mL ) were placed, under a nitrogen atmosphere and stirred for 12 hours at 170 C.. The reaction mixture was extracted with ethyl acetate, washed with water, and dried over anhydrous sodium sulfate. Ethyl acetate was distilled off under reduced pressure and purified by silica gel column chromatography to give 1-(difluoromethyl)-4-nitrobenzene (compound 5b) was obtained in 79% yield
  • 2
  • 1,1,1,3,3-pentafluoro-3-(4-nitrophenyl)propane-2,2-diol [ No CAS ]
  • [ 29848-57-5 ]
  • [ 206360-56-7 ]
 

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[ 206360-56-7 ]

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