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Chemical Structure| 20637-02-9 Chemical Structure| 20637-02-9

Structure of 20637-02-9

Chemical Structure| 20637-02-9

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Product Details of [ 20637-02-9 ]

CAS No. :20637-02-9
Formula : C11H13NO4
M.W : 223.23
SMILES Code : O=C(OC)CCCC1=CC=C([N+]([O-])=O)C=C1
MDL No. :MFCD00517542

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* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 20637-02-9 ]

[ 20637-02-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 20637-02-9 ]
  • [ 20637-09-6 ]
YieldReaction ConditionsOperation in experiment
88% With hydrogen;palladium on activated charcoal; In methanol; for 3h; b) Methyl 4-(4-aminophenyl)butanoateA suspension of methyl 4-(4-nitrophenyl)butanoate (3.05 g, 13.67 mmol) and Pd/C (1.0 g, 10percent Pd on activated C, 1.09 mmol) in MeOH (40 ml_) was stirred under H2 atmosphere (balloon) for 3 h. The reaction mixture was filtered through Celite (washing with EtOAc). Solvent was concentrated off, to furnish 2.33 g of methyl 4-(4-aminophenyl)butanoate (brown solid, yield: 88percent). It was submitted to next step without purification.1H NMR (CDCI3, 250 MHz) delta ppm: 6.96 (d, J = 8.5 Hz, 2H), 6.63 (d, J = 8.2 Hz, 2H), 3.66 (s, 3H), 2.55 (t, J = 7.6 Hz, 2H), 2.31 (t, J = 7.7 Hz, 2H), 1.90 (q, J = 7.6 Hz, 2H).
 

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