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Chemical Structure| 20718-17-6 Chemical Structure| 20718-17-6

Structure of 20718-17-6

Chemical Structure| 20718-17-6

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Product Details of [ 20718-17-6 ]

CAS No. :20718-17-6
Formula : C10H12O2S
M.W : 196.27
SMILES Code : O=C(C1=CC=CC=C1)[CH-][S+](C)(C)=O
MDL No. :N/A

Safety of [ 20718-17-6 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314
Precautionary Statements:P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P403+P233-P501
Class:8
UN#:1759
Packing Group:

Application In Synthesis of [ 20718-17-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 20718-17-6 ]

[ 20718-17-6 ] Synthesis Path-Downstream   1~5

  • 1
  • [ 1019-85-8 ]
  • [ 20718-17-6 ]
  • [ 1417818-96-2 ]
YieldReaction ConditionsOperation in experiment
81% With silver hexafluoroantimonate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; acetic acid; In 1,2-dichloro-ethane; at 130℃; for 18h;Schlenk technique; Sealed tube; General procedure: A 20 mL Schlenk tube equipped with a stir bar was charged with the respective substituted 2-aryl-1H-benzo[d]imidazole (0.2 mmol, 1.0equiv), the corresponding α-aroyl sulfoxonium ylide (0.3 mmol, 1.5equiv), [Cp*RhCl2]2 (6.2 mg, 5 mol%), AgSbF6 (13.7 mg, 20 mol%),AcOH (0.4 mmol, 2.0 equiv), and DCE (2.0 mL). The tube was sealedwith a PTFE cap. The reaction mixture was stirred at 130 C for 18 hunder air in an oil bath. After the completion of the reaction, the mix-ture was then allowed to warm to r.t. and sat. aq NaHCO3 (2 mL) was added. The aqueous layer was extracted with EtOAc (3 × 5 mL). The combined organic extracts were washed with brine (5 mL), dried(MgSO4), and concentrated. The residue obtained was purified byflash column chromatography on silica gel with a mixture of PE andEtOAc (5:1) to give the desired product 3.
  • 2
  • [ 25365-71-3 ]
  • [ 20718-17-6 ]
  • (11H-benzo[a]carbazol-5-yl)(phenyl)methanone [ No CAS ]
YieldReaction ConditionsOperation in experiment
86% With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium acetate; In tetrahydrofuran; at 100℃; for 12h;Sealed tube; 1a (0.5 mmol, 110.6 mg), tetrahydrofuran (3 mL), 2a (1 mmol) were sequentially added to a 15 mL reaction tube.196.3 mg), [RhCp*Cl2] 2 (0.03 mmol, 18.5 mg)And cesium acetate (0.25 mmol, 48.0 mg),Seal the reaction tube under air conditions,The reaction was then stirred in a 100 C oil bath for 12 h. After the reaction is completed, the reaction tube is cooled to room temperature.Add 10 mL of water and extract with ethyl acetate (10 mL x 3).The organic phase is then washed sequentially with water and saturated brine.Dry over anhydrous sodium sulfate. Filter, spin dry,The product was isolated as a yellow solid (38.2 g, 86%).
  • 3
  • [ 55577-25-8 ]
  • [ 20718-17-6 ]
  • 3-methyl-6-phenyl-11H-benzo[a]carbazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
58% With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium acetate; In tetrahydrofuran; at 100℃; for 12h;Sealed tube; 1 g (0.5 mmol, 103.6 mg) was sequentially added to a 15 mL reaction tube.Tetrahydrofuran (3 mL), 2a (0.75 mmol, 147.2 mg),[RhCp*Cl2] 2 (0.025 mmol, 15.4 mg) and cesium acetate (0.25 mmol, 48.0 mg),The reaction tube was sealed under air, and then stirred in an oil bath at 100 C for 12 h.After the completion of the reaction, the reaction tube was cooled to room temperature, and 10 mL of water was added thereto, followed by extraction with ethyl acetate (10 mL × 3), and the organic phase was washed successively with water and brine, and dried over anhydrous sodium sulfate.Filter, spin dry, and separated on silica gel column (petroleum ether / ethyl acetate = 20/1)The yellow liquid product was obtained as 3 g (89.1 mg, 58%).
  • 4
  • [ 20718-17-6 ]
  • [ 52562-19-3 ]
  • [ 37864-30-5 ]
  • 5
  • [ 20718-17-6 ]
  • [ 4596-92-3 ]
  • (6-chloroquinoline-2,3-diyl)bis(phenylmethanone) [ No CAS ]
YieldReaction ConditionsOperation in experiment
26% With silver trifluoromethanesulfonate; copper; In N,N-dimethyl-formamide; at 90℃; for 12.0h;Schlenk technique; The preparation method is as follows: <strong>[4596-92-3]5-<strong>[4596-92-3]chlorobenzo[c]isoxazole</strong></strong> (0.2 mmol, 30.7 mg), Benzoyl oxysulfide ylide (0.3 mmol, 58.8 mg), copper (0.02 mmol, 1.3 mg) and silver triflate (0.02 mmol, 5.1 mg) were added to a 25 ml Schlenk tube. N,N-dimethylformamide (2 ml) was added, and the mixture was stirred at 90 C for 12 hours. After the reaction is completed, 100-200 mesh column chromatography silica gel is added. The solvent was distilled off under reduced pressure, and the crude product was separated by silica gel column chromatography. And eluted with a mixture of petroleum ether and ethyl acetate (petroleum ether: ethyl acetate = 25:1). The TLC elution tracking test is used to collect the eluate containing the target product. Combining the target product eluates, evaporation and concentration gave the 2,3-diacylquinoline compound shown in the above figure in a yield of 26%. This material is a yellow solid, m.p. 144-146.
 

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