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Chemical Structure| 214201-64-6 Chemical Structure| 214201-64-6

Structure of 214201-64-6

Chemical Structure| 214201-64-6

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Product Details of [ 214201-64-6 ]

CAS No. :214201-64-6
Formula : C7H7BrClN5
M.W : 276.52
SMILES Code : NC1=NC(Cl)=C2N=CN(CCBr)C2=N1
MDL No. :MFCD23703078

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Application In Synthesis of [ 214201-64-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 214201-64-6 ]

[ 214201-64-6 ] Synthesis Path-Downstream   1~1

  • 1
  • 3-(acetyloxy)-2-(bromozincio)propyl acetate [ No CAS ]
  • [ 214201-64-6 ]
  • [ 97845-60-8 ]
YieldReaction ConditionsOperation in experiment
80 g In tetrahydrofuran; at 50 - 60℃; for 10h;Inert atmosphere; (4) Add 375ml of tetrahydrofuran and 75g of 2-amino-6-chloro-9-bromoethyl hydrazine to the reaction flask under nitrogen protection.Add the newly prepared catalyst, heat to 50-60 C, slowly add the newly prepared zinc reagent, and drop the reaction at 50-60 C.10h, cool down to 15 ~ 20 C, add 10ml of ethanol, stir for 2h. Concentrate to dryness under reduced pressure, add dichloromethane (500ml), water 300ml50 ml of glacial acetic acid, stirred for 20 to 30 minutes, layered, the organic layer was washed twice with sodium bicarbonate solution, and then washed twice with water, thickAfter shrinking, the concentrate is recrystallized from ethanol and dried under reduced pressure.2-amino-6-chloro-9-(4-acetoxy-3-acetoxymethylbutylBase) 80g or so, HPLC purity of 99.5% or more.
 

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