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Chemical Structure| 2211-57-6 Chemical Structure| 2211-57-6

Structure of 2211-57-6

Chemical Structure| 2211-57-6

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Product Details of [ 2211-57-6 ]

CAS No. :2211-57-6
Formula : C8H11N3
M.W : 149.19
SMILES Code : NC(NCC1=CC=CC=C1)=N
MDL No. :MFCD00461648

Safety of [ 2211-57-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 2211-57-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2211-57-6 ]

[ 2211-57-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1458-01-1 ]
  • [ 2211-57-6 ]
  • [ 2898-76-2 ]
YieldReaction ConditionsOperation in experiment
In methanol; for 2h;Reflux; Inert atmosphere; The guanidine base was dissolved in anhydrousmethanol (2?3 mL/mmol) with methyl 3,5-diamino-6-chloropyrazine-2-carboxylate (1 eq.) and refluxed for2 h under N2 atmosphere. The mixture was cooled toroom temperature, concentrated under reduced pressure,and purified by silica-gel column chromatography(Wako gel® C-200, 10percent methanol/chloroform) toafford series 3 (yield: 23?28percent). The spectral data of3a?3c were listed in the Supporting Information.
 

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