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Structure of 2215-21-6

Chemical Structure| 2215-21-6

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Product Details of [ 2215-21-6 ]

CAS No. :2215-21-6
Formula : C13H18O3
M.W : 222.28
SMILES Code : OC1=C(C(C)C)C=C(C(C)C)C=C1C(O)=O
MDL No. :MFCD00008884
InChI Key :XUFUYOGWFZSHGE-UHFFFAOYSA-N
Pubchem ID :30543

Safety of [ 2215-21-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 2215-21-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2215-21-6 ]

[ 2215-21-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 2215-21-6 ]
  • [ 2934-05-6 ]
YieldReaction ConditionsOperation in experiment
~ 100% With quinoline; for 4h; [00045] 2,4-Diisopropyl-phenol (Intermediate 1) [00046] A mixture of 3,5-diisopropylsalicylic acid (Intermediate 9, 25 g, 0.11 mol, available from Aldrich) and quinoline (50 mL) was refluxed for 4 h. The mixture was cooled to room temperature, diluted with EtOAc (200 mL), washed with 1M HCl (2×200 mL) until acidic, then with brine, dried over Na2SO4, and concentrated in vacuo. The residue was purified by flash column chromatography on silica gel (5% then 10% EtOAc-hexanes) to yield the title compound as a yellow oil (20 g, 100%). [00047] 1H NMR (300 MHz, CDCl3): 1.23 (d, J=6.7 Hz, 6H), 1.27 (d, J=6.7 Hz, 6H), 2.84 (m, 1H), 3.19 (m, 1H), 4.55 (br d, 1H), 6.68 (d, J=8.2 Hz, 1H), 6.83 (dd, J=8.2, 2.3 Hz, 1H), 7.05 (d, J=2.3 Hz, 1H).
 

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