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Chemical Structure| 22717-56-2 Chemical Structure| 22717-56-2

Structure of 22717-56-2

Chemical Structure| 22717-56-2

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Product Details of [ 22717-56-2 ]

CAS No. :22717-56-2
Formula : C8H7BrO3
M.W : 231.04
SMILES Code : O=C(OC)C1=CC=C(Br)C=C1O
MDL No. :MFCD07780736
InChI Key :JEMVEVUWSJXZMX-UHFFFAOYSA-N
Pubchem ID :13983552

Safety of [ 22717-56-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P280-P305+P351+P338-P310

Application In Synthesis of [ 22717-56-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 22717-56-2 ]

[ 22717-56-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 79756-81-3 ]
  • [ 22717-56-2 ]
  • [ 1364266-91-0 ]
  • 2
  • [ 22717-56-2 ]
  • [ 126717-59-7 ]
  • 1‐(4‐bromo-2-hydroxyphenyl)‐2‐(3‐bromo-6-methoxypyridine-2‐yl)ethanone [ No CAS ]
YieldReaction ConditionsOperation in experiment
91.2% Add 250g of tetrahydrofuran to a three-necked flask at room temperature, add 85g of <strong>[126717-59-7]3-bromo-6-methoxy-2-methylpyridine</strong>, add 25.2g of sodium hydroxide in batches with stirring, warm to 60 C, stir for 40 minutes, slowly a mixed solution of 97.2 g of methyl 4-bromosalicylate and 97.2 g of tetrahydrofuran was added dropwise, and the temperature was controlled at 60 C, and the reaction was stirred for 6 hours with stirring. The reaction was complete by TLC. The temperature was lowered, and the reaction liquid was poured into 1 L of water, suction filtered, and dried to give 153.6 g. Yield 91.2%, purity: 96.0%.
 

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