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Chemical Structure| 23158-06-7 Chemical Structure| 23158-06-7

Structure of 23158-06-7

Chemical Structure| 23158-06-7

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Product Details of [ 23158-06-7 ]

CAS No. :23158-06-7
Formula : C10H10O4
M.W : 194.18
SMILES Code : O=C(C1=C2OCOC2=CC=C1)OCC
MDL No. :MFCD06204345

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Application In Synthesis of [ 23158-06-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 23158-06-7 ]

[ 23158-06-7 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 23158-06-7 ]
  • [ 5768-39-8 ]
YieldReaction ConditionsOperation in experiment
95%
Stage #1: With water; sodium hydroxide In methanol at 20℃; for 3.5 h;
Stage #2: With hydrogenchloride In methanol; water
To a solution of the compound of the previous step (16 g) in methanol (170 ml) was added a solution of sodium hydroxide (9.9 g) in water (40 ml), and the mixture was stirred at room temperature for 3.5 hr.
The reaction solution was acidified with concentrated hydrochloric acid, and the mixture was concentrated.
The resulting precipitate was collected by filtration to give the title compound (13 g, 95percent).
NMR(300MHz, CDCl3)δ:6.14(2H, s), 6.90(1H, t, J=7.8Hz), 7.03(1H, dd, J=7.5, 1.2Hz), 7.46(1H, dd, J=8.1, 1.2Hz).
References: [1] Patent: EP2116538, 2009, A1, . Location in patent: Page/Page column 49.
 

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