Purity | Size | Price | VIP Price | USA Stock *0-1 Day | Global Stock *5-7 Days | Quantity | |||||
{[ item.p_purity ]} | {[ item.pr_size ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} |
{[ getRatePrice(item.pr_usd, 1,1) ]} | Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate) ]} | {[ item.pr_usastock ]} | Inquiry - | {[ item.pr_chinastock ]} | Inquiry - |
* Storage: {[proInfo.prStorage]}
CAS No. : | 2325-10-2 | MDL No. : | MFCD00064255 |
Formula : | C14H14O2 | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | IHPDTPWNFBQHEB-KBPBESRZSA-N |
M.W : | 214.26 | Pubchem ID : | 853020 |
Synonyms : |
|
Signal Word: | Warning | Class: | N/A |
Precautionary Statements: | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 | UN#: | N/A |
Hazard Statements: | H302-H315-H319-H335 | Packing Group: | N/A |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
96% | Stage #1: cis-stilben With osmium(VIII) oxide; potassium carbonate; potassium hexacyanoferrate(III) In water; <i>tert</i>-butyl alcohol at 20℃; Stage #2: With ethyl vinyl ether In water; <i>tert</i>-butyl alcohol at 20℃; for 1h; | |
94% | With Hydroquinone 1,4-phthalazinediyl diether; potassium carbonate; potassium hexacyanoferrate(III) In <i>tert</i>-butyl alcohol at 20℃; for 8h; | |
89% | With AD-mix-α; methanesulfonamide In water; <i>tert</i>-butyl alcohol at 0℃; |
85% | With osmium(VIII) oxide; potassium carbonate; potassium hexacyanoferrate(III) In water; toluene; <i>tert</i>-butyl alcohol at 0℃; for 24h; | |
74% | With 4-methyl-morpholine; osmium(VIII) oxide; dihydrogen peroxide In acetone at 20℃; | |
Multi-step reaction with 2 steps 1: 99 percent / aq. K2[OsO2(OH)4]; (DHQ)2PHAL; K3[Fe(CN)6] / K2CO3 / 2-methyl-propan-2-ol / 12 h / 20 °C 2: aq. H2O2 / ethyl acetate; acetone / 20 °C |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
70% | With dmap; dicyclohexyl-carbodiimide In dichloromethane for 24h; Inert atmosphere; |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
69% | at 110℃; for 0.75h; | Procedure for the preparation of ligand6: A mixture of P(NEt2)3 (1) (2.74 ml, 10 mmol) and (S,S)-hydrobenzoin (3) (2.14 g, 10 mmol) was stirred at 110 °C for 45 min. Next the mixture was stirred under vacuum (10 Torr, 90 °C) for 30 min to remove HNEt2 and cooled to 20 °C. The residue was purified by bulb-to-bulb distillation in vacuum (Tbath = 171-182 °C, 1 Torr) and then by flash chromatography on aluminum oxide (toluene).Comment(4S,5S)-2-Diethylamino-4,5-diphenyl-1,3,2-dioxaphospholan (6): White waxy solid; yield 2.18 g (69%); Rf 0.7 (EtOAc/hexane, 1:1, Alugram Alox N/UV254). 1H NMR (400.13 MHz, CDCl3, 25 °C): δ = 1.19 (t, J = 8.0 Hz, 6H, CH3); 3.27 (m, 4H, NCH2); 4.84 (br s, 2H, OCH); 7.19-7.35 (m, 10H, CHAr). 13{H} NMR (100.6 MHz, CDCl3, 25 °C): δC = 15.4 (d, 3J = 4.0 Hz, H3); 38.4 (d, 2J = 28.2 Hz, NH2); 82.6 (d, 2J = 9.1 Hz, OH); 84.7 (d, 2J = 8.1 Hz, OH); 126.4 (s, CHAr); 127.2 (s, CHAr); 128.2 (s, CHAr); 128.3 (s, CHAr); 128.4 (s, CHAr); 128.5 (s, CHAr); 136.7 (d, 3J = 6.0 Hz, CAr); 138.1 (d, 3J = 10.1 Hz, CAr). MS (EI, 70 eV): m/z (%) = 315 (8) [M]+, 181 (100) [PhCH2CHPh] +. Anal. Calcd for C18H22NO2P: C, 68.56; H, 7.03; N, 4.44. Found: C, 68.71; H, 7.16; N, 4.54. |
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
With pyridinium p-toluenesulfonate; In toluene; for 14h;Dean-Stark; Reflux; | A solution of (S,S)-(-)-hydrobenzoin (7.54 g, 35.2 mmol), methyl 3-oxocyclopentanecarboxylate (5 g, 35.2 mmol), and pyridinium p-toluenesulfonate (0.884 g, 3.52 mmol) in toluene (50 ml) was refluxed with a Dean-Stark trap for 14 hours. The reaction was then cooled and partitioned between ethyl acetate and water. The organic was dried over sodium sulfate, filtered and the filtrate evaporated. The crude was purified by silica gel chromatography, eluting with 25 % EtOAc in hexanes to get the title compound. |
[ 196605-90-0 ]
(1S,2S)-1,2-Bis(3,5-dimethylphenyl)ethane-1,2-diol
Similarity: 1.00
[ 579-43-1 ]
rel-(1R,2S)-1,2-Diphenylethane-1,2-diol
Similarity: 1.00
[ 655-48-1 ]
cis-1,2-Diphenylethane-1,2-diol
Similarity: 1.00
[ 52340-78-0 ]
(1R,2R)-1,2-Diphenylethane-1,2-diol
Similarity: 1.00
[ 196605-90-0 ]
(1S,2S)-1,2-Bis(3,5-dimethylphenyl)ethane-1,2-diol
Similarity: 1.00
[ 579-43-1 ]
rel-(1R,2S)-1,2-Diphenylethane-1,2-diol
Similarity: 1.00
[ 655-48-1 ]
cis-1,2-Diphenylethane-1,2-diol
Similarity: 1.00
[ 52340-78-0 ]
(1R,2R)-1,2-Diphenylethane-1,2-diol
Similarity: 1.00