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Chemical Structure| 2362-79-0 Chemical Structure| 2362-79-0

Structure of 2362-79-0

Chemical Structure| 2362-79-0

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Product Details of [ 2362-79-0 ]

CAS No. :2362-79-0
Formula : C13H10ClN
M.W : 215.68
SMILES Code : ClC1=CC=C(C=C1)/C=N/C2=CC=CC=C2
MDL No. :MFCD00018761

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Application In Synthesis of [ 2362-79-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2362-79-0 ]

[ 2362-79-0 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 3167-63-3 ]
  • [ 2362-79-0 ]
  • [ 125112-30-3 ]
  • [ 125112-30-3 ]
  • 2
  • [ 120-72-9 ]
  • [ 2362-79-0 ]
  • [ 178946-89-9 ]
YieldReaction ConditionsOperation in experiment
98% With zinc perchlorate; 1,3-bis[5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-ylmethyleneamino]thiourea; In dichloromethane; at 20℃; for 10h; General procedure: A mixture of ligand L3 (0.005g, 0.01 mmol) and Zn(ClO4)2·6H2O (0.004 g, 0.01 mmol) in CH2Cl2 (2 mL) was stirred at room temperature for 0.5 h. Then, indole (0.023g, 0.2mmol) and imine (0.018g, 0.1 mmol) were added. After the reaction was completed as determined by TLC, the crude mixture was purified by column chromatography on silica gel (ethyl acetate/petroleum ether 1:20-1:10) to afford the desired pure product 3a in 97% yield.
  • 3
  • [ 2362-79-0 ]
  • [ 95-54-5 ]
  • [ 1019-85-8 ]
YieldReaction ConditionsOperation in experiment
89% With iron(III) nitrate nonahydrate; In acetonitrile; at 80℃; for 12h; General procedure: A mixture of 1.5 mmol o-phenylenediamine, and 1 mmol imine, 5 mol% Fe(NO3)3·9H2O, and 5 ml MeCN were mixed in a 10 ml three-necked flask, one necked is equiped with a condenser, another is equiped with a thermometer with a condenser, and then stirred rapidiy open to air at 80C for 12 hours. The reaction progress was monitored by TLC. After completion of the reaction, the residue was directly purified by column chromatograph on a silica gel using hexane/ethyl acetate (7:3) as eluent to afford the pure product.
 

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