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Chemical Structure| 244104-55-0 Chemical Structure| 244104-55-0

Structure of 244104-55-0

Chemical Structure| 244104-55-0

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Product Details of [ 244104-55-0 ]

CAS No. :244104-55-0
Formula : C7H6ClIO
M.W : 268.48
SMILES Code : IC1=CC(Cl)=CC=C1CO
MDL No. :MFCD11847259

Safety of [ 244104-55-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 244104-55-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 244104-55-0 ]

[ 244104-55-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 201230-82-2 ]
  • [ 244104-55-0 ]
  • [ 19641-29-3 ]
YieldReaction ConditionsOperation in experiment
81% With triethylamine; In acetonitrile; at 250℃; under 49403.3 Torr; for 16h;Autoclave; General procedure: A magnetic stirring bar, 2-iodobenzyl alcohol (1a, 116.0 mg, 0.5 mmol), NEt3 (251.6 mg, 2.5 mmol), and MeCN (10 mL) were placed in a stainless steel autoclave equipped with an inserted Pyrex glass liner. The autoclave was closed, purged three times with carbon monoxide, pressurized with 65 atm of CO and then heated at 250 C by salt bath with stirring for 16 h. After the reaction, excess CO was discharged at room temperature. The solvent was removed under reduced pressure, and the residue was purified by flash chromatography on silica gel (hexane/EtOAc = 3/1) to give 2a (60.4 mg, 91%) as a white solid.
 

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