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Chemical Structure| 247186-56-7 Chemical Structure| 247186-56-7

Structure of 247186-56-7

Chemical Structure| 247186-56-7

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Product Details of [ 247186-56-7 ]

CAS No. :247186-56-7
Formula : C12H14O3
M.W : 206.24
SMILES Code : O=C(OC(C)(C)C)C1=CC=CC(C=O)=C1
MDL No. :MFCD02180885
InChI Key :GGPVOXVKIVXELX-UHFFFAOYSA-N
Pubchem ID :10845940

Safety of [ 247186-56-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 247186-56-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 247186-56-7 ]

[ 247186-56-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1791-13-5 ]
  • [ 247186-56-7 ]
  • (S)-di-tert-butyl 2-((3-(tert-butoxycarbonyl)benzyl)amino)succinate [ No CAS ]
YieldReaction ConditionsOperation in experiment
856.4 mg A) (S)-Di-tert-butyl 2-((3-(tert-butoxycarbonyl)benzyl)amino) succinate Acetic acid (0.535 mL) was added to a mixture of <strong>[1791-13-5]L-aspartic acid di-t-butyl ester hydrochloride</strong> (1053 mg), tert-butyl 3-formylbenzoate (771 mg), and THF (20 mL) at room temperature, followed by stirring at the same temperature for 1 hour. Sodium triacetoxyborohydride (1981 mg) was added to the reaction mixture at room temperature, followed by stirring at the same temperature overnight. A saturated sodium hydrogen carbonate aqueous solution was added to the reaction mixture at 0 C., followed by extraction with ethyl acetate. The organic layer was washed with a saturated saline solution and was then dried over anhydrous magnesium sulfate, and the solvent was distilled under reduced pressure. The residue was purified by silica gel column chromatography (NH, ethyl acetate/hexane) to obtain the title compound (856.4 mg). MS: [M+H]+ 436.2.
 

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Technical Information

• Acyl Group Substitution • Barbier Coupling Reaction • Baylis-Hillman Reaction • Benzylic Oxidation • Birch Reduction • Blanc Chloromethylation • Bouveault-Blanc Reduction • Bucherer-Bergs Reaction • Catalytic Hydrogenation • Clemmensen Reduction • Complex Metal Hydride Reductions • Corey-Chaykovsky Reaction • Corey-Fuchs Reaction • Ester Cleavage • Fischer Indole Synthesis • Friedel-Crafts Reaction • Grignard Reaction • Hantzsch Dihydropyridine Synthesis • Henry Nitroaldol Reaction • Horner-Wadsworth-Emmons Reaction • Hydride Reductions • Hydrogenolysis of Benzyl Ether • Julia-Kocienski Olefination • Knoevenagel Condensation • Leuckart-Wallach Reaction • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Mukaiyama Aldol Reaction • Nozaki-Hiyama-Kishi Reaction • Passerini Reaction • Paternò-Büchi Reaction • Petasis Reaction • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Aldehydes and Ketones • Preparation of Alkylbenzene • Preparation of Amines • Prins Reaction • Reactions of Aldehydes and Ketones • Reactions of Amines • Reactions of Benzene and Substituted Benzenes • Reactions with Organometallic Reagents • Reformatsky Reaction • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Specialized Acylation Reagents-Carbodiimides and Related Reagents • Stetter Reaction • Stobbe Condensation • Tebbe Olefination • Ugi Reaction • Vilsmeier-Haack Reaction • Wittig Reaction • Wolff-Kishner Reduction

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