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Chemical Structure| 24903-85-3 Chemical Structure| 24903-85-3

Structure of 24903-85-3

Chemical Structure| 24903-85-3

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Product Details of [ 24903-85-3 ]

CAS No. :24903-85-3
Formula : C8H10N2O3
M.W : 182.18
SMILES Code : O=[N+](C1=CN=C(OC(C)C)C=C1)[O-]
MDL No. :MFCD07374880

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Application In Synthesis of [ 24903-85-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 24903-85-3 ]

[ 24903-85-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 24903-85-3 ]
  • [ 57260-71-6 ]
  • [ 193902-78-2 ]
YieldReaction ConditionsOperation in experiment
4.94 g In ethanol; at 70℃; for 16h; To a solution of 2-chloro-5-nitropyridine (LXXIV) (2.0 g, 12.6 mmol) in EtOH (20 mL) was added tert-butyl piperazine-1-carboxylate (XC) (7.05 g, 37.9 mmol). The reaction was headed at 70 C. for 16 h. The reaction was concentrated under vacuum and then dissolved in EtOAc. The EtOAc was washed with 1 M NaOH, brine and then dried over MgSO4 to give tert-butyl 4-(5-nitropyridin-2-yl)piperazine-1-carboxylate (XCI) as a yellow solid (4.94 g). ESIMS found for C14H20N4O4 m/z 309.0 (M+H).
 

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