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Chemical Structure| 252758-93-3 Chemical Structure| 252758-93-3

Structure of 252758-93-3

Chemical Structure| 252758-93-3

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Product Details of [ 252758-93-3 ]

CAS No. :252758-93-3
Formula : C12H18N2
M.W : 190.28
SMILES Code : NC1=CC=CC=C1N2CC(C)CCC2
MDL No. :MFCD04970971

Safety of [ 252758-93-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Application In Synthesis of [ 252758-93-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 252758-93-3 ]

[ 252758-93-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 5555-00-0 ]
  • [ 252758-93-3 ]
  • 2-methyl-N-(2-(3-methylpiperidin-1-yl)phenyl)furan-3-carboxamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
76% General procedure: A solution of 2-(piperidin-1-yl)aniline (0.2 g, 0.025 mol), dichloromethane (25 mL) and triethylamine (0.5 mL) was added to a 50 mL flask and cooled to 0 C in an ice bath. After ten minutes, 2-chloronicotinoyl chloride (0.22 g) was added [20,21]. The mixture was stirred for 30 min, and then concentrated under reduced pressure to give a crude product. The pure 2-chloro-N-(2-(piperidin-1-yl)phenyl) nicotinamide (1b) was obtained by column chromatography (EtOAc:PE = 8:1) purification yield 88%;
 

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