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[ CAS No. 2557-78-0 ]

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type HazMat fee
Excepted Quantity Free
Inaccessible (Haz class 6.1), Domestic USD 41.00
Inaccessible (Haz class 6.1), International USD 64.00
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 83.00
Accessible (Haz class 3, 4, 5 or 8), International USD 133.00
2D
Chemical Structure| 2557-78-0
Chemical Structure| 2557-78-0
Structure of 2557-78-0 *Storage: {[proInfo.prStorage]}

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Product Details of [ 2557-78-0 ]

CAS No. :2557-78-0MDL No. :MFCD00041419
Formula : C6H5FS Boiling Point : 162.7°C at 760 mmHg
Linear Structure Formula :-InChI Key :N/A
M.W :128.17Pubchem ID :-
Synonyms :

Computed Properties of [ 2557-78-0 ]

TPSA : - H-Bond Acceptor Count : -
XLogP3 : - H-Bond Donor Count : -
SP3 : - Rotatable Bond Count : -

Safety of [ 2557-78-0 ]

Signal Word:DangerClass:3,6.1
Precautionary Statements:P210-P240-P242-P243-P261-P264-P270-P271-P280-P301+P310-P303+P361+P353-P304+P340-P305+P351+P338-P311-P330-P363-P370+P378-P403+P233-P405-P501UN#:1228
Hazard Statements:H225-H301-H311-H315-H319-H331-H335Packing Group:
GHS Pictogram:

Application In Synthesis of [ 2557-78-0 ]

  • Upstream synthesis route of [ 2557-78-0 ]
  • Downstream synthetic route of [ 2557-78-0 ]

[ 2557-78-0 ] Synthesis Path-Upstream   1~6

  • 1
  • [ 2557-78-0 ]
  • [ 2905-21-7 ]
Reference: [1] Green Chemistry, 2017, vol. 19, # 9, p. 2286 - 2295
  • 2
  • [ 2557-78-0 ]
  • [ 14135-38-7 ]
YieldReaction ConditionsOperation in experiment
45% With C17H14O*Pd*C26H24P2S2 In melt at 100℃; for 6 h; Inert atmosphere; Green chemistry General procedure: The melt of catalyst (5 mole percent) and appropriate aryl thiophenol (1 equiv.) was stirred under N2 atmosphere at 100 °C for 6 hours. The progress of reaction was monitored by thin layer chromatography. After 6 hours the reaction mixture was diluted with ethyl acetate and filtered through a sintered glass funnel. The filtrate was further washed with brine (X 3) and dried over Na2SO4 and concentrated under reduced pressure. The oily mass obtained was purified by column chromatography using hexane afford the desired compounds 2a-k.
Reference: [1] Advanced Synthesis and Catalysis, 2015, vol. 357, # 10, p. 2180 - 2186
[2] Organic Letters, 2018, vol. 20, # 19, p. 6274 - 6278
[3] Tetrahedron Letters, 1990, vol. 31, # 35, p. 5007 - 5010
[4] Tetrahedron Letters, 2017, vol. 58, # 6, p. 527 - 530
[5] Patent: WO2007/39741, 2007, A1, . Location in patent: Page/Page column 33-34
[6] Tetrahedron Letters, 2015, vol. 56, # 29, p. 4305 - 4307
[7] Organic and Biomolecular Chemistry, 2014, vol. 12, # 47, p. 9557 - 9561
[8] ChemistryOpen, 2016, vol. 5, # 4, p. 315 - 318
[9] Chemical Communications, 2017, vol. 53, # 90, p. 12197 - 12200
  • 3
  • [ 2557-78-0 ]
  • [ 1259375-01-3 ]
  • [ 1259375-10-4 ]
  • [ 14135-38-7 ]
Reference: [1] Chinese Journal of Chemistry, 2010, vol. 28, # 9, p. 1623 - 1629
  • 4
  • [ 2557-78-0 ]
  • [ 30058-40-3 ]
Reference: [1] Organic and Biomolecular Chemistry, 2016, vol. 14, # 29, p. 6951 - 6954
  • 5
  • [ 2557-78-0 ]
  • [ 1027345-07-8 ]
Reference: [1] Patent: WO2017/101851, 2017, A1,
  • 6
  • [ 2557-78-0 ]
  • [ 1027345-08-9 ]
Reference: [1] Patent: WO2017/101851, 2017, A1,
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