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Chemical Structure| 265321-06-0 Chemical Structure| 265321-06-0

Structure of 265321-06-0

Chemical Structure| 265321-06-0

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Product Details of [ 265321-06-0 ]

CAS No. :265321-06-0
Formula : C5H7NO2
M.W : 113.11
SMILES Code : NC1=CC(=O)COC1
MDL No. :MFCD19204386

Safety of [ 265321-06-0 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H314
Precautionary Statements:P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P403+P233-P501
Class:8
UN#:3259
Packing Group:

Application In Synthesis of [ 265321-06-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 265321-06-0 ]

[ 265321-06-0 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 17115-51-4 ]
  • [ 77771-02-9 ]
  • [ 265321-06-0 ]
  • 9-(3-bromo-4-fluoro-phenyl)-3a-hydroxy-1,1-dioxo-1,2,3,3a,4,5,9,9a-octahydro-6-oxa-1λ6-thia-4-aza-cyclopenta[<i>b</i>]naphthalen-8-one [ No CAS ]
  • 2
  • [ 77771-02-9 ]
  • [ 265321-06-0 ]
  • [ 50607-30-2 ]
  • 10-(3-bromo-4-fluorophenyl)-3,4,6,10-tetrahydro-2H-pyrano[3,4-b][1,6]naphthyridine-1,9(5H,8H)-dione [ No CAS ]
  • 3
  • [ 17115-51-4 ]
  • [ 77771-02-9 ]
  • [ 265321-06-0 ]
  • [ 265320-48-7 ]
  • 4
  • [ 34328-61-5 ]
  • [ 265321-06-0 ]
  • [ 50607-30-2 ]
  • 10-(3-chloro-4-fluorophenyl)-3,4,6,10-tetrahydro-2H-pyrano[3,4-b][1,6]naphthyridine-1,9(5H,8H)-dione [ No CAS ]
YieldReaction ConditionsOperation in experiment
In ethanol; EXAMPLE 44 10-(3-chloro-4-fluorophenyl)-3,4,6,10-tetrahydro-2H-pyrano [3,4-b][1,6]naphthyridine-1,9(5H,8H)-dione A mixture of the product from Example 11C (0.023 g, 0.2 mmol), <strong>[50607-30-2]piperidine-2,4-dione</strong> (Nakagawa, S., Heterocycles (1979), 13, 477-495) (0.23 g, 0.2 mmol), 3-chloro-4-fluorobenzaldehyde (0.032 g, 0.2 mmol) and ethanol (2 mL) was heated to 80° C. for 60 hours and cooled to ambient temperature. The resulting solid was collected by filtration, washed with ethanol and dried under vacuum to provide the title compound. MS (APCI(+)) m/z 349 (M+H)+; MS (APCI(-)) m/z 347 (M-H)-; 1H NMR (DMSO-d6) delta 2.34-2.57 (m, 2H), 3.13-3.28 (m, 2H), 4.00 (s, 2H), 4.45 (AB q, 2H), 4.96 (s, 1H), 7.08 (d, 1H), 7.17 (ddd, 1H), 7.26 (t, 1H), 7.28 (dd, 1H), 9.55 (s, 1H).
 

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