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Chemical Structure| 26819-07-8 Chemical Structure| 26819-07-8

Structure of 26819-07-8

Chemical Structure| 26819-07-8

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Product Details of [ 26819-07-8 ]

CAS No. :26819-07-8
Formula : C10H13NO
M.W : 163.22
SMILES Code : CC1=CC(C(NCC)=O)=CC=C1
MDL No. :MFCD00496601

Safety of [ 26819-07-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362-P403+P233-P501

Application In Synthesis of [ 26819-07-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 26819-07-8 ]

[ 26819-07-8 ] Synthesis Path-Downstream   1~3

  • 1
  • m-toluic acid diethylammonium salt [ No CAS ]
  • [ 134-62-3 ]
  • [ 26819-07-8 ]
YieldReaction ConditionsOperation in experiment
81%; 9% With tetrabutoxytitanium; at 200℃; under 15001.5 Torr; for 0.0333333h;microwave irradiation;Product distribution / selectivity; Example 3Preparation of N,N-diethyl-m-toluamide with Catalysis by Titanium Tetrabutoxide 2 g of diethylamine were admixed slowly with 1 g of m-toluic acid with cooling. After the exothermicity had abated, the ammonium salt thus obtained was admixed with 30 mg of titanium tetrabutoxide and exposed to microwave irradiation of 150 W in a closed cuvette with maximum cooling performance for 2 minutes. A temperature of 200 C. measured by means of an IR sensor was attained; the pressure rose to 20 bar. Subsequently, the reaction mixture was cooled to 30 C. within 2 minutes.In the resulting crude product, 81% of the toluic acid had been converted to N,N-diethyl-m-toluamide and a further 9% to N-ethyl-m-toluamide. After removal of the water of reaction and reirradiation, and subsequent distillative removal of water and excess diethylamine, 90% N,N-diethyl-m-toluamide was obtained. No toluene was detectable as a thermal cleavage product. The iodine color number of the resulting product was 4.
  • 2
  • [ 134-62-3 ]
  • [ 72236-22-7 ]
  • [ 26819-07-8 ]
  • N-ethyl-4-hydroxy-3-methylphenylamide [ No CAS ]
  • N,N-diethyl-trihydroxy-3-methylphenylamide [ No CAS ]
  • [ 15789-04-5 ]
  • [ 108898-76-6 ]
  • [ 85630-34-8 ]
YieldReaction ConditionsOperation in experiment
In water; at 20℃;UV-irradiation; Photolysis; Photolysis experiments were carried out in quartz cells containing DEET at 10, 20 or 40mgL-1 (52, 104 or 208muM) and illumination was provided by a Philips Ultraviolet Light Bulb 15 Watt TUV G15 T8 lamp with emission maximum at 254nm. Temperature within the cell was controlled by a thermostatic bath and fixed at +20C, 0C or -15C. In the case of photolysis in ice, DEET solutions were frozen overnight at -15C before illumination.
  • 3
  • [ 134-62-3 ]
  • [ 72236-22-7 ]
  • [ 26819-07-8 ]
  • N-ethyl-4-hydroxy-3-methylphenylamide [ No CAS ]
  • N,N-diethyl-tetrahydroxy-3-methylphenylamide [ No CAS ]
  • [ 15789-04-5 ]
  • [ 108898-76-6 ]
  • [ 85630-34-8 ]
YieldReaction ConditionsOperation in experiment
In water; at 0℃;UV-irradiation; Photolysis; Photolysis experiments were carried out in quartz cells containing DEET at 10, 20 or 40mgL-1 (52, 104 or 208muM) and illumination was provided by a Philips Ultraviolet Light Bulb 15 Watt TUV G15 T8 lamp with emission maximum at 254nm. Temperature within the cell was controlled by a thermostatic bath and fixed at +20C, 0C or -15C. In the case of photolysis in ice, DEET solutions were frozen overnight at -15C before illumination.
 

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