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Chemical Structure| 27049-45-2 Chemical Structure| 27049-45-2

Structure of 27049-45-2

Chemical Structure| 27049-45-2

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Product Details of [ 27049-45-2 ]

CAS No. :27049-45-2
Formula : C13H11NO
M.W : 197.23
SMILES Code : O=C(CC1=CC=CC=C1)C1=NC=CC=C1
MDL No. :MFCD00023484

Safety of [ 27049-45-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 27049-45-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 27049-45-2 ]

[ 27049-45-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 27049-45-2 ]
  • [ 178686-24-3 ]
  • [ 57-13-6 ]
  • [ 1283117-69-0 ]
YieldReaction ConditionsOperation in experiment
30.2% With hydrogenchloride; In ethanol; water; for 60.0h;Reflux; 00205] A mixture of 2-phenyl-l-(pyridin-2-yl)ethanone (Intermediate 27) (200 mg,1.01 mmol), <strong>[178686-24-3]3-ethoxy-4-hydroxy-5-nitrobenzaldehyde</strong> (214.1 mg, 1.01 mmol), urea (182.5 mg, 3.04 mmol), and concentrated hydrochloric acid solution (0.3 mL) in ethanol (1 mL) was refluxed for 60 h. After being cooled down to room temperature, the mixture was evaporated, and purified by preparative HPLC to give Compound 59 (132.5 mg, yield 30.2%). 1H NMR (DMSO- 6 400MHz): (510.26 (brs, 1H), 8.59 (d, J = 4.4 Hz, 1H), 8.37 (s, 1H), 7.62-7.54 (m, 2H), 7.42 (s, 1H), 7.30-7.27 (m, 1H), 7.14 (d, J = 6.4 Hz, 4H), 6.93-6.90 (m, 3H), 5.25 (s, 1H), 4.03-3.99 (m, 2H), 1.33-1.29 (m, 3H); MS (ESI): m/z 433.0 [M+H]+.
  • 2
  • [ 27049-45-2 ]
  • [ 68500-37-8 ]
  • 4-benzyl-7-methoxyquinoline [ No CAS ]
 

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