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Chemical Structure| 27395-93-3 Chemical Structure| 27395-93-3

Structure of 27395-93-3

Chemical Structure| 27395-93-3

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Product Details of [ 27395-93-3 ]

CAS No. :27395-93-3
Formula : C14H9NO2
M.W : 223.23
SMILES Code : O=CC1=CC=C(C2=NC3=CC=CC=C3O2)C=C1
MDL No. :MFCD00440630

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Application In Synthesis of [ 27395-93-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 27395-93-3 ]

[ 27395-93-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 27395-93-3 ]
  • [ 1190-39-2 ]
  • [ 638990-46-2 ]
YieldReaction ConditionsOperation in experiment
With morpholine; toluene-4-sulfonic acid; In xylene; for 120h;Heating / reflux; A 50 ml three necked reaction flask, equipped with a reflux condenser combined with a water separator and an oil bath with a magnetic stirrer, was charged with 2.3g (10mmol) of 4-benzoxazol-2-yl-benzaldehyde, 2.6g (1.1 mmol) of <strong>[1190-39-2]di-n-butylmalonate</strong>, 0.25 ml of morpholine and 0.17g of p-toluene-sulfonic acid in 30 ml of xylene. After five days under reflux mainly the desired product was detected with HPLC. The reaction mixture was diluted with ethylacetate and washed with water and NaCl solution, dried with Na2SO4 and concentrated to yield 4.9g of a brown honey. Chromatography in hexane/ethylacetate (9:1 to 1:1 v/v) and furnished 1.5g of a yellow liquid. UV (ethanol) 329 nm (E=758), MS: 421 (M+,100%).This product is miscible with Cetiol LC. It was irradiated in high dilution with a Hg-lamp 150 W from Heraeus and has been shown to be photostable.
 

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