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Chemical Structure| 2746-23-8 Chemical Structure| 2746-23-8

Structure of 2746-23-8

Chemical Structure| 2746-23-8

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Product Details of [ 2746-23-8 ]

CAS No. :2746-23-8
Formula : C5H5ClS
M.W : 132.61
SMILES Code : ClCC1=CSC=C1
MDL No. :MFCD08445657

Safety of [ 2746-23-8 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H312-H332-H335-H314
Precautionary Statements:P260-P264-P270-P271-P280-P301+P330+P331-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P403+P233-P405-P501
Class:8
UN#:3265
Packing Group:

Application In Synthesis of [ 2746-23-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2746-23-8 ]

[ 2746-23-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 2746-23-8 ]
  • [ 4983-28-2 ]
  • 2-chloro-5-(thien-3-ylmethoxy)pyrimidine [ No CAS ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In N-methyl-acetamide; water; (2) A mixture of <strong>[4983-28-2]2-chloro-5-hydroxypyrimidine</strong> (200 mg), 3-chloromethylthiophene (610 mg), potassium carbonate (635 mg) and dimethylformamide (3 ml) is stirred at 50° C. for one hour. After the reaction is complete, to the reaction mixture is added water, and extracted with ethyl acetate. The organic layer is washed with water and saturated brine, dried, and concentrated under reduced pressure. The residue is purified by silica gel column chromatography (solvent; n-hexane/ethyl acetate=20:1-->20:3), and evaporated to remove the solvent to give 2-chloro-5-(3-thienylmethoxy)pyrimidine (345 mg) as colorless needles. M.p. 73°-76° C.
 

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