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Chemical Structure| 3010-03-5 Chemical Structure| 3010-03-5

Structure of 3010-03-5

Chemical Structure| 3010-03-5

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Product Details of [ 3010-03-5 ]

CAS No. :3010-03-5
Formula : C7H12N2
M.W : 124.18
SMILES Code : N#CCN1CCCCC1
MDL No. :MFCD00023733

Safety of [ 3010-03-5 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301+H311+H331-H315-H319
Precautionary Statements:P261-P264-P270-P271-P280-P301+P310+P330-P302+P352+P312+P361+P364-P304+P340+P311-P305+P351+P338+P337+P313-P403+P233-P405-P501
Class:6.1
UN#:3439
Packing Group:

Application In Synthesis of [ 3010-03-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3010-03-5 ]

[ 3010-03-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3010-03-5 ]
  • 4-phenoxybenzenediazonium tetrafluoroborate [ No CAS ]
  • [ 3096-81-9 ]
YieldReaction ConditionsOperation in experiment
85% With 1,1,1,2,2,2-hexamethyldisilane; palladium diacetate; tert-butyl alcohol; In tetrahydrofuran; at 55℃; for 48h;Schlenk technique; General procedure: A mixture of Pd(OAc)2 (0.02 mmol, 7.2 mg, 10 mol%), t-BuOH (0.4mmol, 7.2 mg, 2.0 equiv), (Me3Si)2 (29.2 mg, 0.2 mmol, 1.0 equiv), 2-(piperidin-1-yl)acetonitrile (3) (25 mg, 0.2 mmol, 1.0 equiv), and thearyldiazonium tetrafluoroborate 2 (0.2 mmol) in THF (1.0 mL) washeated with stirring at 55 C for 48 h in a Schlenk tube (25 mL) underan air atmosphere. The cooled solution was diluted, extracted withEtOAc/H2O, and washed with brine. The organic layer was dried overNa2SO4, filtered and concentrated in vacuo. The crude residue was purifiedby flash silica gel column chromatography to afford the correspondingcyanated product.
References: [1]Synthesis,2022.
 

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