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Chemical Structure| 304690-95-7 Chemical Structure| 304690-95-7

Structure of 304690-95-7

Chemical Structure| 304690-95-7

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Product Details of [ 304690-95-7 ]

CAS No. :304690-95-7
Formula : C11H13F3N2O2S
M.W : 294.29
SMILES Code : O=S(C(F)(F)F)(NC1=CC2=C(C=C1)CCCN2C)=O
MDL No. :MFCD11112070

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Application In Synthesis of [ 304690-95-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 304690-95-7 ]

[ 304690-95-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 304690-95-7 ]
  • [ 64837-53-2 ]
  • C16H17F3N6O4S2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
In 84 g of acetic acid, 72 g of phosphoric acid, and 28 g of sulfuric acid was dissolved 12.2 g of 2-amino-5-ethoxycarbonyl-1,3,4-thiadiazole (structural formula 1a). This solution was cooled to 5°C or lower. Thereto was added dropwise 22 g of 43percent nitrosylsulfuric acid. Thus, a solution of a diazo compound of 2-amino-5-ethoxycarbonyl-1,3,4-thiadiazole was prepared. Subsequently, the diazo compound solution obtained above was added dropwise to a solution composed of 8.6 g of the compound represented by the following structural formula 1b and 172 mL of methanol under the conditions of 5°C or lower, and the resultant mixture was stirred for 2 hours. This mixture was then neutralized with 28percent ammonia water. Thereafter, the crystals precipitated were taken out by filtration and purified to obtain 20 g of the azo compound represented by the following structural formula 1c.
 

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