Alternatived Products of [ 31867-92-2 ]
Product Details of [ 31867-92-2 ]
CAS No. : | 31867-92-2 |
MDL No. : | MFCD18258906 |
Formula : |
C10H9ClN2
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
192.64
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 31867-92-2 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 31867-92-2 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 31867-92-2 ]
- 1
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[ 52537-00-5 ]
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[ 31867-92-2 ]
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4-(6-Chloro-2,3-dihydro-indol-1-yl)-6,7-dimethyl-quinazoline
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
16% |
|
Example 95 4-(6-Chloro-2,3-dihydro-indol-1-yl)-6,7-dimethyl-quinazoline Utilizing a procedure analogous to that described in Example 24, this product was prepared in 16% yield from <strong>[52537-00-5]6-chloro-indoline</strong> and 4-chloro-6,7-dimethyl-quinazoline. (M.P. 199 C.; LC-MS: 310 (MH+)). |
- 2
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[ 2243-47-2 ]
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[ 31867-92-2 ]
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(6,7-dimethylquinazolin-4-yl)-(biphenyl-3'-yl)amine hydrochloride
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
85% |
In isopropyl alcohol at 80℃; for 0.25h; Microwave irradiation; |
General procedure for 4-anilinoquinazolines 5-18, 34-36
General procedure: A mixture of 4-chloroquinazoline (23a-c,[1] 23d-f, 31-33[3]) (0.5 mmol) and the appropriate aniline (0.5 mmol) in i-PrOH (1 mL) was microwave irradiated at 80 °C (power set point 60 W; ramp time1 min; hold time 15 min). After cooling, the obtained precipitate was collected by filtration to give compounds 5-18 and 33-35 as hydrochlorides. |
Reference:
[1]Conconi, Maria Teresa; Marzaro, Giovanni; Urbani, Luca; Zanusso, Ilenia; Di Liddo, Rosa; Castagliuolo, Ignazio; Brun, Paola; Tonus, Francesca; Ferrarese, Alessandro; Guiotto, Adriano; Chilin, Adriana
[European Journal of Medicinal Chemistry, 2013, vol. 67, p. 373 - 383]