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Chemical Structure| 32333-31-6 Chemical Structure| 32333-31-6

Structure of 32333-31-6

Chemical Structure| 32333-31-6

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Product Details of [ 32333-31-6 ]

CAS No. :32333-31-6
Formula : C6H12N2O4
M.W : 204.27
SMILES Code : CC(C1=CC(CCC(C)(C)O2)=C2C=C1)=O
MDL No. :MFCD00277400

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* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 32333-31-6 ]

[ 32333-31-6 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 19013-07-1 ]
  • [ 32333-31-6 ]
YieldReaction ConditionsOperation in experiment
97% With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; at 20℃; To a solution of (chloro[2-(di-tert-butylphosphino)biphenyl] gold(I) (15 mg, 5 mol %) and AgSbF6(9.8 mg, 5 mol %) in anhydrous dichloromethane (2 mL) was added S1 (107 mg, 0.53 mmol) and the reaction stirred at rt for 15 min. The solvent was then removed in vacuo and the residue purified by chromatography (hexanes:ethyl acetate, 9:1→1:1) to give the product as a yellow oil (211 mg, 66%yield). Rf 0.66 (hexanes-ethyl acetate, 7:3); 1H NMR (CDCl3, 400 MHz) δ 1.45 (s, 6H), 2.52 (s, 3H),5.66 (d, 1H, J = 11 Hz), 6.35 (d, 1H, J = 11 Hz), 6.78 (d, 1H, J = 8.2 Hz), 7.61 (s, 1H), 7.75 (d, 1H,J = 8.2 Hz). Data were in agreement with that previously reported.iiiThe chromene product (211 mg, 1.04 mmol) was dissolved in THF (20 mL), 10% Pd/C (27 mg)added and the reaction mixture stirred under a hydrogen atmosphere (balloon) for 2.5 h. The mixturewas then filtered through Celite and the solvent removed in vacuo to give the desired chroman S2 asa white solid (204 mg, 97%)
 

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