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Chemical Structure| 3342-78-7 Chemical Structure| 3342-78-7

Structure of 3342-78-7

Chemical Structure| 3342-78-7

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Product Details of [ 3342-78-7 ]

CAS No. :3342-78-7
Formula : C8H9NO2
M.W : 151.16
SMILES Code : O=C(O)CC1=CC=CC=C1N
MDL No. :MFCD03701521
InChI Key :KHMNCHDUSFCTGK-UHFFFAOYSA-N
Pubchem ID :583776

Safety of [ 3342-78-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H319
Precautionary Statements:P305+P351+P338

Application In Synthesis of [ 3342-78-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3342-78-7 ]

[ 3342-78-7 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 3342-78-7 ]
  • [ 18698-99-2 ]
  • 2
  • [ 3342-78-7 ]
  • [ 151-50-8 ]
  • [ 18698-99-2 ]
  • 3
  • [ 67-56-1 ]
  • [ 3342-78-7 ]
  • [ 35613-44-6 ]
YieldReaction ConditionsOperation in experiment
With thionyl chloride; at 0 - 20℃; 2-(2-(3,4-Dichloro-N-methylphenylsulfonamido)phenyl)-acetic acid S2; Thionyl chloride (5.2 ml, 71.4 mmol) was added dropwise, with stirring and while cooling with ice, to a solution of 2-aminophenylacetic acid (7.2 g, 47.6 mmol) in methanol (150 ml). The reaction mixture was stirred overnight at room temperature. The reaction solution was concentrated, and thionyl chloride residues were removed by dragging out with toluene and DCM. 10.3 g (contaminated with starting material) of the were obtained in the form of a brown solid. The crude product was used further without being purified further.
  • 4
  • [ 3342-78-7 ]
  • [ 124-41-4 ]
  • [ 35613-44-6 ]
YieldReaction ConditionsOperation in experiment
82.75% In methanol; at 60 - 70℃; for 10h; Add 2- (2-aminophenyl) acetic acid (0.79 g, 5.2 mmol) andSodium methoxide (0.30g, 5.5mmol)Dissolved in methanol (10mL),Stir for 10h at 60 70 ,Methyl 2- (2-aminophenyl) acetate (white solid, 0.71 g) was obtained in a yield of 82.75%.
 

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