[ CAS No. 3347-62-4 ] {[proInfo.proName]}

Name: 3347-62-4|3-Methyl-5-phenyl-1H-pyrazole|95%
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Quality Control of [ 3347-62-4 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 3347-62-4 ]

SDS Specification

Alternatived Products of [ 3347-62-4 ]

Product Details of [ 3347-62-4 ]

CAS No. :	3347-62-4	MDL No. :	MFCD00022385
Formula :	C₁₀H₁₀N₂	Boiling Point :	-
Linear Structure Formula :	C₆H₅C₃H₂N₂(CH₃)	InChI Key :	QHRSESMSOJZMCO-UHFFFAOYSA-N
M.W :	158.20	Pubchem ID :	18774
Synonyms :		Chemical Name :	3-Methyl-5-phenyl-1H-pyrazole

Calculated chemistry of [ 3347-62-4 ] Expand+

Physicochemical Properties

Num. heavy atoms :	12
Num. arom. heavy atoms :	11
Fraction Csp3 :	0.1
Num. rotatable bonds :	1
Num. H-bond acceptors :	1.0
Num. H-bond donors :	1.0
Molar Refractivity :	48.99
TPSA :	28.68 Å²

Pharmacokinetics

GI absorption :	High
BBB permeant :	Yes
P-gp substrate :	No
CYP1A2 inhibitor :	Yes
CYP2C19 inhibitor :	No
CYP2C9 inhibitor :	No
CYP2D6 inhibitor :	No
CYP3A4 inhibitor :	No
Log Kp (skin permeation) :	-5.65 cm/s

Lipophilicity

Log Po/w (iLOGP) :	1.57
Log Po/w (XLOGP3) :	2.28
Log Po/w (WLOGP) :	2.39
Log Po/w (MLOGP) :	1.77
Log Po/w (SILICOS-IT) :	3.06
Consensus Log Po/w :	2.21

Druglikeness

Lipinski :	0.0
Ghose :	None
Veber :	0.0
Egan :	0.0
Muegge :	1.0
Bioavailability Score :	0.55

Water Solubility

Log S (ESOL) :	-2.87
Solubility :	0.214 mg/ml ; 0.00135 mol/l
Class :	Soluble
Log S (Ali) :	-2.52
Solubility :	0.478 mg/ml ; 0.00302 mol/l
Class :	Soluble
Log S (SILICOS-IT) :	-4.13
Solubility :	0.0118 mg/ml ; 0.0000748 mol/l
Class :	Moderately soluble

Medicinal Chemistry

PAINS :	0.0 alert
Brenk :	0.0 alert
Leadlikeness :	1.0
Synthetic accessibility :	1.77

Safety of [ 3347-62-4 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P261-P305+P351+P338	UN#:	N/A
Hazard Statements:	H302-H315-H319-H335	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 3347-62-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 3347-62-4 ]

[ 3347-62-4 ] Synthesis Path-Downstream 1~109

1
[ 110-91-8 ]
[ 79815-53-5 ]
[ 79815-71-7 ]
[ 3347-62-4 ]

Reference： [1]Journal of Organic Chemistry,1982,vol. 47,p. 295 - 300

2
[ 77202-05-2 ]
[ 77202-10-9 ]
[ 3347-62-4 ]

Reference： [1]Chemical and Pharmaceutical Bulletin,1990,vol. 38,p. 1524 - 1526
[2]Chemical and pharmaceutical bulletin,1988,vol. 36,p. 3838 - 3848

3
[ 90861-40-8 ]
[ 3347-62-4 ]

Reference： [1]Journal of the Chemical Society. Perkin transactions I,1984,p. 611 - 614

4
[ 82755-33-7 ]
[ 3347-62-4 ]

Reference： [1]Journal of Organic Chemistry USSR (English Translation),1984,vol. 20,p. 1361 - 1364
Zhurnal Organicheskoi Khimii,1984,vol. 20,p. 1494 - 1497

5
[ 3347-62-4 ]
[ 1087-09-8 ]
[ 92670-68-3 ]

Reference： [1]Journal of Organic Chemistry,1984,vol. 49,p. 4647 - 4656

6
[ 3347-62-4 ]
[ 77202-10-9 ]

Reference： [1]Journal of Organic Chemistry,1985,vol. 50,p. 5520 - 5523

7
[ 3347-62-4 ]
[ 77202-05-2 ]
[ 99214-42-3 ]

Reference： [1]Journal of Organic Chemistry,1985,vol. 50,p. 5520 - 5523

8
[ 3347-62-4 ]
[ 84691-22-5 ]

Reference： [1]Synthesis,1982,p. 844 - 846

9
[ 75-03-6 ]
[ 3347-62-4 ]
[ 851427-81-1 ]
1-ethyl-3-methyl-5-phenyl-1H-pyrazole [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
123 mg; 56 mg	With sodium hydroxide; In acetonitrile; at 20℃; for 2h;	General procedure: A mixture of (E)-4-phenylbut-3-en-2-one (1e) (146 mg, 1.0 mmol) and TsNHNH2 (205 mg, 1.1 mmol) in CH3CN (2 mL) were stirred at room temperature for 3 h and then CH3CN (2 mL), NaOH (44 mg, 1.1 mmol) were added and the mixture was heated at reflux for 17 h, then NaOH (60 mg, 1.5 mmol) and benzyl bromide (255 mg, 1.5 mmol) were subsequently added and the mixture was stirred at room temperature for 2 h. The product was extracted with Et2O and the organic layer was washed with brine, dried over anhydrous MgSO4, filtered, and concentrated in vacuo. Purification by chromatography on silica gel afforded the desired product 4s as white crystalline solid (194 mg, 78% yield).

Reference： [1]Tetrahedron,2005,vol. 61,p. 12377 - 12385
[2]Tetrahedron,2013,vol. 69,p. 1427 - 1433

10
[ 629-27-6 ]
[ 3347-62-4 ]
[ 851427-87-7 ]
3-methyl-1-octyl-5-phenyl-1H-pyrazole [ No CAS ]

Reference： [1]Tetrahedron,2005,vol. 61,p. 12377 - 12385

11
[ 111-83-1 ]
[ 3347-62-4 ]
[ 851427-87-7 ]
3-methyl-1-octyl-5-phenyl-1H-pyrazole [ No CAS ]

Reference： [1]Tetrahedron,2005,vol. 61,p. 12377 - 12385

12
[ 107-06-2 ]
[ 3347-62-4 ]
1-(2-chloroethyl)-5-methyl-3-phenylpyrazole [ No CAS ]
1-(2-chloroethyl)-3-methyl-5-phenylpyrazole [ No CAS ]

Reference： [1]Heterocycles,2005,vol. 65,p. 1691 - 1704

13
[ 106-93-4 ]
[ 3347-62-4 ]
1-(2-bromoethyl)-5-methyl-3-phenylpyrazole [ No CAS ]
1-(2-bromoethyl)-3-methyl-5-phenylpyrazole [ No CAS ]
1,2-bis(5-methyl-3-phenylpyrazol-1-yl)ethane [ No CAS ]

Reference： [1]Heterocycles,2005,vol. 65,p. 1691 - 1704

14
[ 3347-62-4 ]
[ 13808-66-7 ]

Yield	Reaction Conditions	Operation in experiment
	With bromine; In dichloromethane; at 0 - 20℃; for 2.5h;	To a solution of 5-methyl-3-phenyl-lH-pyrazole (8.0 g, 50.6 mmol) in dichloromethane(150 mL) was added bromine (8.08 g, 50.6 mmol) dropwise at 0 0C. The reaction was stirred at that temperature for 30 min and continued at room temperature for 2 h. After the reaction was quenched with an aqueous solution OfNa2SO3 (10% w/w, 10 mL), the organic solvent was removed and the aqueous mixture was extracted with EtOAc, washed with brine, dried over MgSO4, and concentrated. The residue was purified by silica gel column chromatography to give the title compound as a yellow oil (9.5 g). LCMS mlz = 236.9 (M+H4). 1H NMR (400 MHz, DMSO-J6) delta ppm 2.26 (s, 3H), 7.30-7.57 (m, 5H), 13.12 (s, IH).

Reference： [1]Tetrahedron,2007,vol. 63,p. 8104 - 8111
[2]Synthesis,1982,p. 844 - 846
[3]Patent: WO2010/68242,2010,A1 .Location in patent: Page/Page column 124
[4]Bioorganic and Medicinal Chemistry Letters,2017,vol. 27,p. 3716 - 3722

15
[ 3347-62-4 ]
[ 863494-35-3 ]

Reference： [1]Heterocycles,2005,vol. 65,p. 1691 - 1704

16
[ 3347-62-4 ]
1-(2-diphenylphosphanyl-phenyl)-5-methyl-3-phenyl-1<i>H</i>-pyrazole [ No CAS ]

Reference： [1]Tetrahedron Letters,2004,vol. 45,p. 9525 - 9528

17
acetophenone (3-imino-1-methyl-3-phenylprop-1-enyl)hydrazone [ No CAS ]
[ 3347-62-4 ]

Reference： [1]Journal of Chemical Research, Miniprint,1985,p. 1478 - 1492

18
[ 94012-44-9 ]
[ 3347-62-4 ]

Reference： [1]Bulletin of the Chemical Society of Japan,1984,vol. 57,p. 2954 - 2956

19
[ 98-86-2 ]
phenylacetaldehyde ; benzaldehyde [ No CAS ]
[ 3347-62-4 ]

Reference： [1]Bulletin of the Chemical Society of Japan,1984,vol. 57,p. 2954 - 2956

20
[ 100-47-0 ]
3-phenyl-1,2-benzisoselenazole [ No CAS ]
[ 3347-62-4 ]

Reference： [1]Journal of the Chemical Society. Perkin transactions I,1984,p. 611 - 614

21
[ 3347-62-4 ]
[ 92670-83-2 ]

Reference： [1]Journal of Organic Chemistry,1984,vol. 49,p. 4647 - 4656

22
[ 3347-62-4 ]
[ 84691-24-7 ]

Reference： [1]Synthesis,1982,p. 844 - 846

23
[ 3347-62-4 ]
[ 84691-25-8 ]

Reference： [1]Synthesis,1982,p. 844 - 846

24
4,4-dimethyl-2,2-dioxo-2λ'-[1,2,3] oxathiazinane-3-carboxylic acid tert-butyl ester [ No CAS ]
[ 865-47-4 ]
[ 3347-62-4 ]
[ 93-91-4 ]
[ 521267-14-1 ]

Yield	Reaction Conditions	Operation in experiment
	With hydrogenchloride; hydrazine; In dichloromethane; N,N-dimethyl-formamide; acetonitrile;	Step C]: [1,1-Dimethyl-3-(5-methyl-3-phenyl-pyrazol-1-yl)-propyl]-carbamic Acid Tert-Butyl Ester 5-Methyl-3-phenyl-1H-pyrazole (320 mg, prepared from benzoylacetone and hydrazine according to Ali et al., Pak. J. Sci. Ind. Res. 1993, 36 (12), 502) was dissolved in DMF (7 ml) and cooled to 0 C. with an ice bath. Potassium-tert-butoxide (284 mg) was added in portions and the mixture was stirred for 45 min at 0 C. Then, 4,4-dimethyl-2,2-dioxo-2lambda'-[1,2,3]oxathiazinane-3-carboxylic acid tert-butyl ester (617 mg) was added in one portion and the reaction mixture was allowed to stir for 20 hours at RT. HCl (1N aqueous solution, 10 ml) was added and stirring was continued for 15 minutes. The mixture was diluted with ether, washed with water and brine (the aqueous layers were re-extracted twice with ether), dried and evaporated. The crude product was purified by flash chromatography (0 to 15% gradient of CH3CN in CH2Cl2) to give the desired product as a yellow gum. Yield: 545 mg. A regioisomer present in minor amounts was removed in the chromatographic purification step. MS (ISP): 344.5 (MH+)

Reference： [1]Patent: US2003/130281,2003,A1

25
sulfimidate [ No CAS ]
[ 3347-62-4 ]
[ 207557-35-5 ]
(2S)-1-[(1S)-1-Methyl-2-(5-methyl-3-phenyl-pyrazol-1-yl)-ethylamino]-acetyl}-pyrrolidine-2-carbonitrile [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
		Example 112 (2S)-1-[(1S)-1-Methyl-2-(5-methyl-3-phenyl-pyrazol-1-yl)-ethylamino]-acetyl}-pyrrolidine-2-carbonitrile The title compound was obtained in analogy to example 78, steps C] to E] from <strong>[3347-62-4]5-methyl-3-phenyl-1H-pyrazole</strong> by replacing sulfimidate XIX with IV and with the exception, that the final coupling step with IIA was done as described in example 1. The title compound was obtained as the free amine as a glass. MS (ISP): 352.4 (MH+).

Reference： [1]Patent: US2003/130281,2003,A1

26
[ 96-09-3 ]
[ 3347-62-4 ]
[ 742097-02-5 ]

Reference： [1]Polish Journal of Chemistry,2007,vol. 81,p. 1987 - 1999

27
[ 20780-53-4 ]
[ 3347-62-4 ]
[ 1073427-17-4 ]
C₁₈H₁₈N₂O [ No CAS ]
2-(5-methyl-3-phenyl-pyrazol-1-yl)-2-phenyl-ethanol [ No CAS ]

Reference： [1]Polish Journal of Chemistry,2007,vol. 81,p. 1987 - 1999

28
[ 3347-62-4 ]
[ 263260-09-9 ]
(4S,5S)-4-(3-phenyl-5-methylpyrazol-1-ylmethyl)-5-(4-methylsulfanyl-phenyl)-2-phenyl-4,5-dihydrooxazole [ No CAS ]

Reference： [1]Polish Journal of Chemistry,2007,vol. 81,p. 1987 - 1999

29
[ 3347-62-4 ]
(4S)-2-chloromethyl-4-ethyl-2-oxazoline [ No CAS ]
C₁₆H₂₁N₃O₂ [ No CAS ]

Reference： [1]Polish Journal of Chemistry,2007,vol. 81,p. 1987 - 1999

30
[ 16940-66-2 ]
[ 49633-25-2 ]
[ 3347-62-4 ]
Na⁽¹⁺⁾*(HB((C₆H₅)(CH₃)C₃HN₂)2((CH₃)2CHC₃H₂N₂))^(1-)=Na(HB((CH₃)(C₆H₅)C₃HN₂)2)((CH₃)2CHC₃H₂N₂) [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 89 - 93

31
pentacarbonyl(1-ethoxy-3-phenylpropyn-1-ylidene)tungsten [ No CAS ]
[ 3347-62-4 ]
[(CO)5W(C(OC₂H₅)CHC(C₆H₅C₃HN₂CH₃)C₆H₅)] [ No CAS ]

Reference： [1]Journal of Organometallic Chemistry,2006,vol. 691,p. 1984 - 1992

32
potassium borohydride [ No CAS ]
thallium(I) nitrate [ No CAS ]
[ 3347-62-4 ]
thallium hydrotris(3-phenyl-5-methylpyrazol-1-yl)borate [ No CAS ]

Reference： [1]Inorganic Chemistry,1994,vol. 33,p. 3666 - 3676

33
potassium borohydride [ No CAS ]
[ 3347-62-4 ]
potassium hydrotris(3-phenyl-5-methyl-pyrazol-1-yl)borate [ No CAS ]

Reference： [1]Inorganica Chimica Acta,2002,vol. 337,p. 459 - 462

34
chloro(1,5-cyclooctadiene)iridium(I) dimer [ No CAS ]
[ 3347-62-4 ]
bis(cycloocta-1,5-diene)bis(μ-3-phenyl-5-methylpyrazolyl)diiridium(I) [ No CAS ]

Reference： [1]Organometallics,1985,vol. 4,p. 1107 - 1114

35
potassium borohydride [ No CAS ]
[ 3347-62-4 ]
[ 51581-48-7 ]
K pyrazolylbis(1-(o-anisyl)-2-thioimidazolyl)borate [ No CAS ]

Reference： [1]Chemical Communications,2001,p. 1026 - 1027

36
[ 16940-66-2 ]
[ 3347-62-4 ]
sodium [hydrotris(3-phenyl-5-methylpyrazolyl)borate] [ No CAS ]
sodium hydrogen bis(5-methyl-3-phenylpyrazol-1-yl) (3-methyl-5-phenylpyrazol-1-yl) borate [ No CAS ]

Reference： [1]Polyhedron,2001,vol. 20,p. 237 - 244
[2]Polyhedron,2001,vol. 20,p. 237 - 244

37
[ 67-51-6 ]
[ 16940-66-2 ]
[ 3347-62-4 ]
sodium [hydrotris(3-phenyl-5-methylpyrazolyl)borate] [ No CAS ]
sodium hydrogen bis(5-methyl-3-phenylpyrazol-1-yl) (3-methyl-5-phenylpyrazol-1-yl) borate [ No CAS ]
sodium [hydrobis(3-methyl-5-phenylpyrazolyl)(3-phenyl-5-methylpyrazolyl)borate] [ No CAS ]

Reference： [1]Polyhedron,2001,vol. 20,p. 2551 - 2558

38
[ 16940-66-2 ]
[ 56426-41-6 ]
[ 3347-62-4 ]
sodium [hydrotris(3-phenyl-5-methylpyrazolyl)borate] [ No CAS ]

Reference： [1]Polyhedron,2002,vol. 21,p. 2743 - 2753

39
N,N-dimethyl-(S)-1-[(R)-2-(diphenylphosphino)ferrocenyl]ethylamine [ No CAS ]
[ 3347-62-4 ]
1-((S)-1-[(R)-2-(diphenylphosphino)ferrocenyl]ethyl)-5-methyl-3-phenyl-1H-pyrazole [ No CAS ]

Reference： [1]Organometallics,1995,vol. 14,p. 5415 - 5425

40
[(norbornadiene)RhCl]2 [ No CAS ]
[ 3347-62-4 ]
[ 167287-02-7 ]

Reference： [1]Polyhedron,1995,vol. 14,p. 1139 - 1148

41
zinc(II) perchlorate [ No CAS ]
[ 3347-62-4 ]
[ 60-24-2 ]
[(2-thiolateethanolate)bis(5-methyl-3-phenyl-pyrazolate)dizinc(II)]6 [ No CAS ]

Reference： [1]Chemical Communications,2003,p. 1278 - 1279

42
[ 109-99-9 ]
[ 39929-21-0 ]
[ 3347-62-4 ]
[Au(μ-3-Me-5-Ph-pz)]3*THF [ No CAS ]

Reference： [1]Inorganic Chemistry,2003,vol. 42,p. 261 - 263

43
[ 2817-73-4 ]
[ 16940-66-2 ]
[ 3347-62-4 ]
[ 503156-57-8 ]

Reference： [1]Polyhedron,2003,vol. 22,p. 581 - 586

44
potassium borohydride [ No CAS ]
[ 3347-62-4 ]
[ 25372-14-9 ]
K⁽¹⁺⁾*[HB(C₃H₂N₂(S)(CH₃C₆H₄))2(C₃HN₂(CH₃)C₆H₅)]^(1-)=K[HB(C₃H₂N₂(S)(CH₃C₆H₄))2(C₃HN₂(CH₃)C₆H₅)] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

45
potassium borohydride [ No CAS ]
[ 3347-62-4 ]
[ 17452-14-1 ]
K⁽¹⁺⁾*[HB(C₃H₂N₂(S)(CH₃OC₆H₄))2(C₃HN₂(CH₃)C₆H₅)]^(1-)=K[HB(C₃H₂N₂(S)(CH₃OC₆H₄))2(C₃HN₂(CH₃)C₆H₅)] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

46
potassium borohydride [ No CAS ]
[ 3347-62-4 ]
[ 51581-48-7 ]
K⁽¹⁺⁾*[HB(C₃H₂N₂(S)(CH₃OC₆H₄))2(C₃HN₂(CH₃)C₆H₅)]^(1-)=K[HB(C₃H₂N₂(S)(CH₃OC₆H₄))2(C₃HN₂(CH₃)C₆H₅)] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

47
potassium borohydride [ No CAS ]
[ 3347-62-4 ]
N-(4-isopropylphenyl)-2-mercaptoimidazole [ No CAS ]
K⁽¹⁺⁾*[HB(C₃H₂N₂(S)((CH₃)2CC₆H₅))2(C₃HN₂(CH₃)C₆H₅)]^(1-)=K[HB(C₃H₂N₂(S)((CH₃)2CC₆H₅))2(C₃HN₂(CH₃)C₆H₅)] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

48
potassium borohydride [ No CAS ]
[ 3347-62-4 ]
[ 60-56-0 ]
K⁽¹⁺⁾*[HB(C₃H₂N₂(S)CH₃)2(C₃HN₂(CH₃)C₆H₅)]^(1-)=K[HB(C₃H₂N₂(S)CH₃)2(C₃HN₂(CH₃)C₆H₅)] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

49
potassium borohydride [ No CAS ]
[ 3347-62-4 ]
[ 17452-09-4 ]
K⁽¹⁺⁾*[HB(C₃H₂N₂(S)(C₆H₅))2(C₃HN₂(CH₃)C₆H₅)]^(1-)=K[HB(C₃H₂N₂(S)(C₆H₅))2(C₃HN₂(CH₃)C₆H₅)] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

50
potassium borohydride [ No CAS ]
[ 3347-62-4 ]
[ 23671-38-7 ]
K⁽¹⁺⁾*[HB(C₃H₂N₂(S)(CH₃C₆H₄))2(C₃HN₂(CH₃)C₆H₅)]^(1-)=K[HB(C₃H₂N₂(S)(CH₃C₆H₄))2(C₃HN₂(CH₃)C₆H₅)] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

51
potassium borohydride [ No CAS ]
[ 3347-62-4 ]
[ 26209-27-8 ]
K⁽¹⁺⁾*[HB(C₃H₂N₂(S)((CH₃)2C₆H₃))2(C₃HN₂(CH₃)C₆H₅)]^(1-)=K[HB(C₃H₂N₂(S)((CH₃)2C₆H₃))2(C₃HN₂(CH₃)C₆H₅)] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

52
[ 67-51-6 ]
[ 16940-66-2 ]
[ 3347-62-4 ]
sodium hydrobis(3-phenyl,5-methylpyrazolyl)(3,5-dimethylpyrazolyl)borate [ No CAS ]

Reference： [1]Polyhedron,2002,vol. 21,p. 2743 - 2753

53
dimethyl((R)-1-[(S)-2-(dibutylphosphino)ferrocenyl]ethyl)amine [ No CAS ]
[ 3347-62-4 ]
1-((R)-1-[(S)-2-(dibutylphosphino)ferrocenyl]ethyl)-5-methyl-3-phenyl-1H-pyrazole [ No CAS ]

Reference： [1]Organometallics,1995,vol. 14,p. 5415 - 5425

54
(HB(N₂C₃H(CH₃)C₆H₅)3)Zn(OC₂H₅) [ No CAS ]
[ 3347-62-4 ]
(HB(N₂C₃H(CH₃)C₆H₅)3)Zn(N₂C₃H(CH₃)C₆H₅) [ No CAS ]

Reference： [1]Inorganic Chemistry,2004,vol. 43,p. 6054 - 6060

55
[ 21264-30-2 ]
[ 3347-62-4 ]
[ 842123-31-3 ]

Reference： [1]Inorganica Chimica Acta,2005,vol. 358,p. 617 - 622

56
[ 13869-38-0 ]
[ 3347-62-4 ]
[ 842123-33-5 ]

Reference： [1]Inorganica Chimica Acta,2005,vol. 358,p. 617 - 622

57
[ 13826-83-0 ]
[RuCl₂(hexamethylbenzene)]2 [ No CAS ]
[ 3347-62-4 ]
[(η6-hexamethylbenzene)Ru(μ-Cl)(3(5)-methyl-5(3)-phenylpyrazole)]2(BF4)2 [ No CAS ]

Reference： [1]Journal of Organometallic Chemistry,2004,vol. 689,p. 3265 - 3274

58
[ 13826-83-0 ]
[ 52462-29-0 ]
[ 3347-62-4 ]
[ 75-05-8 ]
[(η6-p-cymene)Ru(3(5)-methyl-5(3)-phenylpyrazole)(1-methylcarbaldimino-3(5)-methyl-5(3)-phenylpyrazole)](BF4)2 [ No CAS ]

Reference： [1]Journal of Organometallic Chemistry,2004,vol. 689,p. 3265 - 3274

59
[ 75-09-2 ]
[Tp(Ph,Me)Zn(acetohydroxamate)] [ No CAS ]
[ 3347-62-4 ]
[Tp(Ph,Me)Zn(acetohydroxamate)(3-methyl-5-phenylpyrazole)]*0.5CH₂Cl₂ [ No CAS ]

Reference： [1]Inorganica Chimica Acta,2007,vol. 360,p. 1523 - 1528

60
[ 403-33-8 ]
[ 3347-62-4 ]
[ 934290-28-5 ]

Yield	Reaction Conditions	Operation in experiment
12%	With 40% KF/Al2O3 ;18-crown-6 ether; In dimethyl sulfoxide; at 120℃; for 48h;	A compound wherein a methyl group was introduced into the 5-position of the pyrazole ring of XO-TT469 was synthesized. A pyrazole, XO-TT485, was prepare by condensation reaction of 1-phenyl-1,3-butanedione and hydrazine. And a 4-phenylcarboxylic acid unit was introduced (the following scheme).; XO-TT486A; XO-TT485 (300 mg, 1.90 mmol) was dissolved in dimethyl sulfoxide (10 mL), and to the solution were added 40% potassium fluoride-alumina (600 mg), methyl 4-fluorobenzoate (492 mL, 3.80 mmol) and 18-crown-6 (100 mg, 0.380 mmol). The mixture was stirred at 120C for 2 days. To the reaction mixture was added water, and the mixture was extracted with ethyl acetate. The residue was purified by column chromatography on silica gel (hexane : ethyl acetate = 10 : 1 to 5 : 1) to give XO-TT486A as a white solid (64.9 mg, 12% yield).

Reference： [1]Patent: EP1932833,2008,A1 .Location in patent: Page/Page column 6; 8

61
[ 3347-62-4 ]
[ 2216-94-6 ]
[ 1083011-10-2 ]

Reference： [1]Zeitschrift fur Naturforschung, B: Chemical Sciences,2008,vol. 63,p. 65 - 70

62
[ 143-66-8 ]
[ 3347-62-4 ]
Na[BP^Ph,Me] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2008,p. 3970 - 3976

63
[ 143-66-8 ]
[ 3347-62-4 ]
2C₁₁H₁₂N₂*C₃₂H₂₈BN₄^(1-)*Na⁽¹⁺⁾ [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2008,p. 3970 - 3976

64
[ 96-49-1 ]
[ 3347-62-4 ]
[ 196810-78-3 ]

Yield	Reaction Conditions	Operation in experiment
59.6%		Sodium hydride (2.5 g, 1.5 g NaH, 62 mmol, 1.1 equiv) is added over aperiod of 3 min to a solution of 5-methyl-3-phenyl-lJ7-pyrazole (9.00 g, 56.9 mmol,1 equiv) in DMF (90 mL) cooled to 0 C in an ice bath. After stilling 15 min, ethylenecarbonate (7.6 mL, 10 g, 110 mmol, 2.0 equiv) is added. The bath is removed, and thereaction mixture is stirred for 15 h. The mixture is treated with 4 M aq K2CO3 (90 mL),heated at reflux for 5 h, and diluted with H2O (200 mL). After allowing the hot mixtureto cool for 15 min, more H2O (100 mL) and then hexanes (100 mL) are added. Themixture is shaken vigorously and then allowed to separate. Crystals formed and stayedwith the top organic layer. The aqueous layer is separated, and the crystals are collectedby vacuum filtration and washed with hexanes (2x50 mL). The crystals are dissolved inEt2O/EtOAc (1:1; 200 mL), and the solution is dried (Na2SO4), filtered, and concentrated(75 C) to give the title compound as an off-white crystalline solid (6.86 g, 59.6%).HRMS Calculated for Ci2Hi5N2O: m/z 203.1 184. Found: 203.1 168

Reference： [1]Patent: WO2005/51945,2005,A1 .Location in patent: Page/Page column 80-81

65
[ 100-07-2 ]
[ 3347-62-4 ]
[ 1187042-71-2 ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2009,vol. 19,p. 4963 - 4966

66
[ 75-36-5 ]
[ 98-86-2 ]
[ 3347-62-4 ]

Yield	Reaction Conditions	Operation in experiment
		To a solution of acetophenone (10 g, 83 mmol) in anhydrous toluene (10 mL) was added LiHMDS (1.0 M in THF, 83 mL, 83 mmol) via syringe at 0 0C under argon. After 5 min, acetyl chloride (6.53 g, 83 mmol) was added in one portion via syringe. The ice bath was removed and glacial AcOH (5 mL), EtOH (50 mL), and hydrazine hydrate (12.50 g, 250 mmol) were added. The mixture was refluxed for 2 h. After cooled to room temperature, the reaction was neutralized to pH 7 by adding 1.0 M NaOH solution. The mixture was extracted with EtOAc, washed with brine, dried over MgSO4, and concentrated. The residue was purified by silica gel column chromatography to give the title compound as a pale yellow oil (12.05 g). LCMS mlz = 159.0 [M+H]+; 1H NMR (400 MHz, DMSO-J6) delta ppm 2.25 (s, 3H), 6.42 (s, IH), 7.20-7.44 (m, 3H), 7.67-7.82 (m, 2H), 12.53 (bs, IH).

Reference： [1]Patent: WO2010/68242,2010,A1 .Location in patent: Page/Page column 124

67
[ 55150-54-4 ]
[ 3347-62-4 ]
1-(5-methyl-3-phenyl-1H-pyrazol-1-yl)-3-phenylisoquinoline [ No CAS ]

Reference： [1]Tetrahedron Letters,2010,vol. 51,p. 4340 - 4343

68
[ 3347-62-4 ]
[ 194292-28-9 ]
3-(4-chlorophenyl)-1-(5-methyl-3-phenyl-1H-pyrazol-1-yl)lisoquinoline [ No CAS ]

Reference： [1]Tetrahedron Letters,2010,vol. 51,p. 4340 - 4343

69
[ 106-38-7 ]
[ 90888-57-6 ]
[ 331974-33-5 ]
[ 3347-62-4 ]

Reference： [1]Advanced Synthesis and Catalysis,2010,vol. 352,p. 3235 - 3240

70
[ 591-50-4 ]
[ 3347-62-4 ]
[ 7188-89-8 ]

Yield	Reaction Conditions	Operation in experiment
36%	With copper(II) acetate monohydrate; caesium carbonate; In N,N-dimethyl-formamide; at 110℃; for 24h;Inert atmosphere;	General procedure: To a solution of Cu(OAc)2·H2O (0.01 mmol) in DMF (2 mL) were added aryl iodide (1.2 mmol), nitrogen-containing heterocycle (1.0 mmol), and Cs2CO3 (2 mmol) under nitrogen atmosphere. The mixture was stirred at 110 C for 24 h. After cooling to ambient temperature, the mixture was partitioned between water and ethyl acetate. The organic layer was separated, and the aqueous layer was extracted with ethyl acetate. The combined organic layers were washed with brine, dried over Na2SO4, and concentrated in vacuo. The residue was purified by flash chromatography on silica gel.

Reference： [1]Tetrahedron,2011,vol. 67,p. 5282 - 5288

71
[ 3347-62-4 ]
HB(CH₃(C₃HN₂)C₆H₅)3Rh(CO)2 [ No CAS ]

Reference： [1]Inorganic Chemistry,1994,vol. 33,p. 3666 - 3676

72
[ 3347-62-4 ]
HB(CH₃(C₃HN₂)C₆H₅)3Pd(CH₂C(CH₃)CH₂) [ No CAS ]

Reference： [1]Inorganic Chemistry,1994,vol. 33,p. 3666 - 3676

73
[ 3347-62-4 ]
bis[hydrotris(3-phenyl,5-methylpyrazolyl)borato]cobalt(II) [ No CAS ]

Reference： [1]Inorganic Chemistry,1994,vol. 33,p. 3666 - 3676

74
[ 3347-62-4 ]
sodium hydrogen bis(5-methyl-3-phenylpyrazol-1-yl) (3-methyl-5-phenylpyrazol-1-yl) borate [ No CAS ]

Reference： [1]Polyhedron,2001,vol. 20,p. 237 - 244
[2]Polyhedron,2001,vol. 20,p. 2551 - 2558

75
[ 3347-62-4 ]
[ 1849-01-0 ]
[ 1332624-73-3 ]
[ 1332624-74-4 ]

Reference： [1]Journal of Organic Chemistry,2011,vol. 76,p. 8262 - 8269

76
[ 100-52-7 ]
[ 3347-62-4 ]

Reference： [1]Tetrahedron,2011,vol. 67,p. 9618 - 9621
[2]Synlett,2018,vol. 29,p. 1071 - 1075

77
[ 122-57-6 ]
[ 3347-62-4 ]

Yield	Reaction Conditions	Operation in experiment
94%	With tetrabutylammomium bromide; toluene-4-sulfonic acid hydrazide; sodium hydroxide; In water; at 80℃; for 10h;Air atmosphere;	General procedure: A Schlenk tube with a magnetic stir bar charged with alpha,beta-unsaturated carbonyl compounds (0.5 mmol, 1 equiv), tosyl hydrazide (0.6 mmol, 1.2 equiv), NaOH (1.5 equiv), (n-Bu)4NBr (1.5 equiv). The reaction vessel was placed in an 80 C oil bath, and then stirring at this temperature for 10 h. The reaction mixture was then allowed to cool to ambient temperature, and diluted with 20 mL of ethyl acetate, and washed with brine (15 mL), water (15 mL), and then the organic layer was dried over Na2SO4. After concentrated in vacuo, the crude product was purified by column chromatography. The identity and purity of the known product was confirmed by 1H NMR, 13C NMR, and GC-MS.
81%	With iodine; potassium carbonate; toluene-4-sulfonic acid hydrazide; In ethanol; at 75℃; for 2h;Green chemistry;	General procedure: To a stirred mixture of alpha,beta-unsaturated aldehydes/ketones 1 (0.5 mmol) and TsNHNH2 (0.6 mmol) in EtOH (2.0 ml) was added molecular iodine (2.5 mg, 2 mol%) in an oven-dried flask, and then the reaction was heated to 75 C for 10 min followed by the addition of K2CO3 immediately. The reaction proceeded under an air atmosphere for 1.5-2.0 h until complete consumption of starting material as monitored by TLC. The reaction mixture was concentrated under vacuum and the crude product was purified by column chromatography using petroleum ether/ethyl acetate as eluent to provide the product 2.

Reference： [1]Tetrahedron,2011,vol. 67,p. 9618 - 9621
[2]Tetrahedron Letters,2016,vol. 57,p. 2633 - 2637
[3]European Journal of Organic Chemistry,2020,vol. 2020,p. 2086 - 2092

78
[ 3347-62-4 ]
bis[hydrobis(3-phenyl,5-methylpyrazolyl)(3-methyl,5-phenylpyrazolyl)borato]copper(II) [ No CAS ]

Reference： [1]Polyhedron,2002,vol. 21,p. 2743 - 2753

79
[ 3347-62-4 ]
bis[hydrobis(3-phenyl,5-methylpyrazolyl)(3-methyl,5-phenylpyrazolyl)borato]cobalt(II) [ No CAS ]

Reference： [1]Polyhedron,2002,vol. 21,p. 2743 - 2753

80
[ 67-51-6 ]
[ 3347-62-4 ]
[hydrobis(3-phenyl,5-methylpyrazolyl)(3,5-dimethylpyrazolyl)borato][hydrotris(3-phenyl,5-methylpyrazolyl)borato]cobalt(II) [ No CAS ]

Reference： [1]Polyhedron,2002,vol. 21,p. 2743 - 2753

81
[ 56426-41-6 ]
[ 3347-62-4 ]
bis[hydrotris(3-phenyl,5-methylpyrazolyl)borato]cobalt(II) [ No CAS ]

Reference： [1]Polyhedron,2002,vol. 21,p. 2743 - 2753

82
[ 3347-62-4 ]
thiocyanatohydrobis(3-phenyl,5-methylpyrazolyl)(3,5-diethylpyrazolyl)boratocobalt lactate [ No CAS ]

Reference： [1]Polyhedron,2003,vol. 22,p. 581 - 586

83
[ 3347-62-4 ]
tetrahydrofuran thiocyanatohydrobis(3-phenyl,5-methylpyrazolyl)(3,5-diethylpyrazolyl)boratocobalt [ No CAS ]

Reference： [1]Polyhedron,2003,vol. 22,p. 581 - 586

84
[ 3347-62-4 ]
methanol-d4 thiocyanatohydrobis(3-phenyl,5-methylpyrazolyl)(3,5-diethylpyrazolyl)boratocobalt [ No CAS ]

Reference： [1]Polyhedron,2003,vol. 22,p. 581 - 586

85
[ 3347-62-4 ]
[hydrobis(3-phenyl,5-methylpyrazolyl)(3,5-diethylpyrazolyl)borato][hydrotris(pyrazolyl)borato]cobalt(II) [ No CAS ]

Reference： [1]Polyhedron,2003,vol. 22,p. 581 - 586

86
[ 3347-62-4 ]
[HB(C₃H₂N₂(S)CH₃)2(C₃HN₂(CH₃)C₆H₅)ZnOH] [ No CAS ]
[(HB(C₃H₂N₂(S)CH₃)2(C₃HN₂(CH₃)C₆H₅))2Zn]*3H₂O [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

87
[ 3347-62-4 ]
[HB(C₃H₂N₂(S)CH₃)2(C₃HN₂(CH₃)C₆H₅)ZnCl] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

88
[ 3347-62-4 ]
[HB(C₃H₂N₂(S)C₆H₅)2(C₃HN₂(CH₃)C₆H₅)ZnCl] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

89
[ 3347-62-4 ]
[HB(C₃H₂N₂(S)C₆H₅)2(C₃HN₂(CH₃)C₆H₅)ZnOH] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

90
[ 3347-62-4 ]
[HB(C₃H₂N₂(S)C₆H₄CH₃)2(C₃HN₂(CH₃)C₆H₅)ZnCl] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

91
[ 3347-62-4 ]
[HB(C₃H₂N₂(S)C₆H₄OCH₃)2(C₃HN₂(CH₃)C₆H₅)ZnCl] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

92
[ 3347-62-4 ]
[HB(C₃H₂N₂(S)C₆H₄CH₃)2(C₃HN₂(CH₃)C₆H₅)ZnONO₂] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

93
[ 3347-62-4 ]
[HB(C₃H₂N₂(S)C₆H₄CH(CH₃)2)2(C₃HN₂(CH₃)C₆H₅)ZnCl] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

94
[ 3347-62-4 ]
[HB(C₃H₂N₂(S)C₆H₃(CH₃)2)2(C₃HN₂(CH₃)C₆H₅)ZnCl] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

95
[ 3347-62-4 ]
[HB(C₃H₂N₂(S)C₆H₄CH(CH₃)2)2(C₃HN₂(CH₃)C₆H₅)ZnONO₂] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

96
[ 3347-62-4 ]
[Zn(HB(C₃H₂N₂SC₆H₄(OCH₃))2(CH₃C₃HN₂(C₆H₅)))(OClO₃)] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

97
[ 3347-62-4 ]
[HB(C₃H₂N₂(S)C₆H₄OCH₃)2(C₃HN₂(CH₃)C₆H₅)ZnONO₂] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

98
[ 3347-62-4 ]
[(HB(C₃H₂N₂(S)C₆H₄CH₃)2(C₃HN₂(CH₃)C₆H₅))2Zn] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

99
[ 3347-62-4 ]
[(HB(C₃H₂N₂(S)C₆H₃(CH₃)2)2(C₃HN₂(CH₃)C₆H₅))2Zn] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

100
[ 3347-62-4 ]
[HB(C₃H₂N₂(S)C₆H₄CH₃)2(C₃HN₂(CH₃)C₆H₅)ZnSC₃H₃N₂C₆H₄CH₃]⁽¹⁺⁾*ClO₄^(1-)=[C₄₀H₃₈BN₈S₃Zn]ClO₄ [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

101
[ 3347-62-4 ]
[HB(C₃H₂N₂(S)C₆H₄OCH₃)2(C₃HN₂(CH₃)C₆H₅)Zn(C₂H₅OH)]⁽¹⁺⁾*ClO₄^(1-)*C₂H₅OH=[C₃₂H₃₄BN₆O₃S₂Zn]ClO₄*C₂H₅OH [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

102
[ 3347-62-4 ]
[HB(C₃H₂N₂(S)C₆H₄CH(CH₃)2)2(C₃HN₂(CH₃)C₆H₅)ZnSC₃H₄N₂C₆H₃CH(CH₃)2]⁽¹⁺⁾*ClO₄^(1-)=[C₄₆H₅₀BN₈S₃Zn]ClO₄ [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

103
[ 3347-62-4 ]
[ 23671-38-7 ]
[(HB(C₃H₂N₂(S)C₆H₄CH₃)2(C₃HN₂(CH₃)C₆H₅))2Zn] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2003,p. 2502 - 2511

104
[ 3347-62-4 ]
[FeCl(thf)(diphenylbis(5-methyl-3-phenyl-1-pyrazolyl)borate)] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2008,p. 3970 - 3976

105
[ 3347-62-4 ]
[Fe(diphenylbis(5-methyl-3-phenyl-1-pyrazolyl))(5-methyl-3-phenylpyrazole)(OCOC(Ph)(C₃HN₂(Me)Ph)OBPh₂)] [ No CAS ]

Reference： [1]European Journal of Inorganic Chemistry,2008,p. 3970 - 3976

106
[ 1571-33-1 ]
[ 3347-62-4 ]
[ 1316892-11-1 ]

Reference： [1]Structural Chemistry,2011,vol. 22,p. 931 - 941

107
[ 67-56-1 ]
[ 88-89-1 ]
[ 3347-62-4 ]
[ 1392829-73-0 ]

Reference： [1]Supramolecular Chemistry,2012,vol. 24,p. 285 - 297

108
bis((2-pyridinyl-κN)phenyl-κ2C)iridium(III) chloride dimer [ No CAS ]
[ 124-41-4 ]
[ 3347-62-4 ]
[(ppy)₂Ir(μ-OH)(μ-PhMePz)Ir(ppy)₂] [ No CAS ]
[(ppy)₂Ir(PhMePz)Cl] [ No CAS ]

Reference： [1]Inorganic Chemistry,2012,vol. 51,p. 10536 - 10547,12

109
bis((2-pyridinyl-κN)phenyl-κ2C)iridium(III) chloride dimer [ No CAS ]
[ 3347-62-4 ]
[(ppy)₂Ir(PhMePz)Cl] [ No CAS ]

Reference： [1]Inorganic Chemistry,2012,vol. 51,p. 10536 - 10547,12

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P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
{[ item.p_purity ]}	{[ item.pr_size ]}	Inquiry	{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price) ]} {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price) ]}	{[ getRatePrice(item.pr_usd, 1,1,item.pr_is_large_size_no_price) ]}	Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price) ]} {[ getRatePrice(item.pr_usd,1,item.mem_rate,item.pr_is_large_size_no_price) ]}	{[ item.pr_usastock ]}		{[ item.pr_chinastock ]}	{[ item.pr_remark ]}

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 3347-62-4 ] {[proInfo.proName]}

Quality Control of [ 3347-62-4 ]

Related Doc. of [ 3347-62-4 ]

Product Details of [ 3347-62-4 ]

Calculated chemistry of [ 3347-62-4 ] Expand+

Physicochemical Properties

Pharmacokinetics

Lipophilicity

Druglikeness

Water Solubility

Medicinal Chemistry

Safety of [ 3347-62-4 ]

Application In Synthesis of [ 3347-62-4 ]

[ 3347-62-4 ] Synthesis Path-Downstream 1~109

Technical Information

Related Functional Groups of [ 3347-62-4 ]

Aryls

Related Parent Nucleus of [ 3347-62-4 ]

Pyrazoles

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry

Related Functional Groups of
[ 3347-62-4 ]

Related Parent Nucleus of
[ 3347-62-4 ]