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Chemical Structure| 34143-74-3 Chemical Structure| 34143-74-3

Structure of 34143-74-3

Chemical Structure| 34143-74-3

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Product Citations

Product Citations

Lusina, Aleksandra ; Jana, Somdeb ; Pattyn, Emiel ; Hoogenboom, Richard ; Cegłowski, Michał ;

Abstract: Perfluorooctanesulfonic acid (PFOS) is a persistent organic pollutant frequently detected in food and environmental samples, posing significant health risks. This study presents an approach for the selective detection and quantification of PFOS in food samples using functionalized poly(2-oxazoline)-based molecularly imprinted polymers (MIPs) coupled with flowing atmospheric pressure afterglow mass spectrometry (FAPA-MS). The MIPs were prepared based on a poly(2-allylamidoethyl-2-oxazoline) precursor polymer that was partially functionalized with different thiols through radical thiol-ene “click” chemistry, followed by cross-linking with bis(2-mercaptoethyl)ether in the presence of PFOS as a template. The resulting MIPs, functionalized with alkyl, hydroxyl, carboxyl, and perfluoroalkyl groups, demonstrated high selectivity and adsorption capacity for PFOS, with carboxyl- and perfluoroalkyl-functionalized MIPs showing the highest adsorption capacities of 375 and 406 mg g-1, respectively. It was demonstrated that the presence of the side-chain amide groups in poly(2-allylamidoethyl-2-oxazoline) leads to more performant MIPs compared to analogues based on poly[2-(3-butenyl)-2-oxazoline]. The MIPs were applied to analyze PFOS in real-life food samples. The detection limits (LODs) for PFOS in these matrices were as low as 5 ppb, with excellent recovery rates. The method exhibited high precision, with relative standard deviations (RSDs) below 8.2% for intraday and interday measurements. This study demonstrates the effectiveness of poly(2-allylamidoethyl-2-oxazoline)-based MIPs for sensitive and selective PFOS detection in complex food matrices, offering a robust tool for food safety and environmental monitoring.

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Product Details of [ 34143-74-3 ]

CAS No. :34143-74-3
Formula : C10H5F17S
M.W : 480.18
SMILES Code : SCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
MDL No. :MFCD00792429
InChI Key :URJIJZCEKHSLHA-UHFFFAOYSA-N
Pubchem ID :542755

Safety of [ 34143-74-3 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H315-H319-H413-H372
Precautionary Statements:P501-P273-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Class:9
UN#:3334
Packing Group:

Application In Synthesis of [ 34143-74-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 34143-74-3 ]

[ 34143-74-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 34143-74-3 ]
  • [ 55894-18-3 ]
  • tri-n-butyl[3-(1H,1H,2H,2H-perfluorodecylthio)propyl]phosphonium bromide [ No CAS ]
YieldReaction ConditionsOperation in experiment
92% With 2,2-dimethoxy-2-phenylacetophenone; In methanol; for 1h;UV-irradiation; Tri-n-butyl(2-propen-1-yl)phosphonium bromide (1.537 g,4.75 mmol), 1H,1H,2H,2H-perfluorodecanethiol (2 eq., 4.513 g,9.40 mmol), and DMPA (0.05 eq., 0.064 g, 0.25 mmol) were combinedin a 20 mL scintillation vial equipped with a magnetic stirbar and dissolved in 7.5 mL methanol to form a colorless solution.The mixture was irradiated under UV light for 1 hr with constantstirring, producing a white suspension. The suspension was transferredto a round bottom flask and solvent was removed via rotaryevaporation. The crude product was stirred with 60 mL hexanes for1 hr at room temperature, forming a mixture with two liquidphases. The top solvent layer was decanted, leaving a viscous oilthat was stirred with an additional 60 mL hexanes at 50 for 1hr. Solvent was again decanted and the purified oil was dried ona vacuum line, eventually affording a white solid that was subsequentlystored in a desiccator. Yield: white solid, 3.522 g, 92%.Melting point (DSC): 46 C. 1H NMR (400 MHz, CD3OD): dH(ppm) = 2.80 (m, 4H), 2.51 (m, 2H), 2.38 (m, 2H), 2.26 (m, 6H),1.88 (m, 2H), 1.55 (m, 12H), 1.01 (t, J = 7.0 Hz, 9H). 13C NMR(101 MHz, CD3OD): dC (ppm) = 33.36 (d, J = 17.3 Hz), 32.91 (t,J = 21.8 Hz), 24.97 (d, J = 15.6 Hz), 24.44 (d, J = 4.6 Hz), 23.29 (t,J = 4.1 Hz), 22.54 (d, J = 3.6 Hz), 19.22 (d, J = 48.5 Hz), 18.49 (d,J = 48.5 Hz), 13.70 (s). 19F NMR (376 MHz, CD3OD): dF (ppm) =-82.38, 115.21, 122.71, 122.89, 123.74, 124.27, 127.28.31P NMR (162 MHz, CD3OD): dP (ppm) = 34.16. HRMS (ESI/QTOF)m/z: [M - Br]+ calculated for C25H37F17PS: 723.2082, found:723.8196. FTIR-ATR (cm1): 2960, 2934, 2909, 2873, 2807, 1465,1450, 1417, 1367, 1330, 1314, 1237, 1199, 1145, 1135, 1115,1085, 1033, 997, 970, 955, 918, 901, 871, 825, 803, 777, 764,745, 737, 725, 705, 684, 657, 621, 619, 605, 595, 587, 580, 573,559, 537, 533.
 

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