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Chemical Structure| 35351-20-3 Chemical Structure| 35351-20-3

Structure of 35351-20-3

Chemical Structure| 35351-20-3

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Product Details of [ 35351-20-3 ]

CAS No. :35351-20-3
Formula : C9H6ClNO2
M.W : 195.60
SMILES Code : O=C(C1=CC2=CC(Cl)=CC=C2O1)N

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Application In Synthesis of [ 35351-20-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 35351-20-3 ]

[ 35351-20-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 110-85-0 ]
  • [ 35351-20-3 ]
  • [ 183288-46-2 ]
YieldReaction ConditionsOperation in experiment
72% With copper dichloride; In dimethyl sulfoxide; at 150℃; Example 1 In 100ml flask was added 5-chloro-benzofuran-2-carboxamide (3.91g,0.02mol), piperazine (3.44g, 0.04mol), copper chloride (0.27g, 0.002mol),And dimethyl sulfoxide (50ml), was heated with stirring at 150C reaction. The reaction was monitored by thin layer chromatography. After the end of the reaction, the solvent was removed, 10ml of diethyl ether was added to the system, with vigorous stirring, to precipitate a solid.The solid was recrystallized from ethyl acetate to give 5-piperazin-yl-benzofuran-2-carboxamide 3.52 g of the, in 72% yield.
 

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