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Chemical Structure| 355116-94-8 Chemical Structure| 355116-94-8

Structure of 355116-94-8

Chemical Structure| 355116-94-8

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Product Details of [ 355116-94-8 ]

CAS No. :355116-94-8
Formula : C13H21NO4
M.W : 255.31
SMILES Code : NC1=CC=C(OCCOCCOCCOC)C=C1

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Application In Synthesis of [ 355116-94-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 355116-94-8 ]

[ 355116-94-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 5926-51-2 ]
  • [ 355116-94-8 ]
  • 1-(4-(2-(2-(2-methoxyethoxy)-ethoxy)ethoxy)phenyl)-3-bromo-1H-pyrrole-2,5-dione [ No CAS ]
YieldReaction ConditionsOperation in experiment
72% With acetic acid; for 3h;Reflux; Inert atmosphere; A solution of <strong>[5926-51-2]bromomaleic anhydride</strong> (0.23 mL, 2.5 minol) and 4-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)aniline21 (588 mg, 2.30 minol) in acetic acid (6 mL), wasstirred at r.t. overnight. The reaction mixture was then heated to reflux for 3 hours and concentrated. The residue was purified by column chromatography (1:1 petroleum ether:ethyl acetate), to provide maleimide 28 (691 mg, 72percent) as a yellow oil.Rf = 0.25 (1:1 petroleum ether:ethyl acetate); 1H NMR (500 MHz, CDCI3): oe 3.37 (3H, 5),3.54 (2H, m), 3.64?3.69 (4H, m), 3.73 (2H, t, J = 4.7 Hz), 3.86 (2H, t, J = 4.7 Hz), 4.14(2H, t, J = 4.9 Hz), 6.98 (2H, d, J = 9.3 Hz), 6.99 (1H, 5), 7.20 (2H, d, J = 9.3 Hz); 13CNMR (125 MHz, CDCI3): oe 59.1, 67.8, 69.6, 70.6, 70.7, 70.9, 72.0, 115.3, 123.8, 127.6,131.7, 131.9, 158.7, 164.5, 167.7; IR: vmax 2874, 1708, 1519, 1145, 1105, 1048 cm1HRMS-ESI: [M + Na] calcd for C17H2079BrNO6Na 436.0366, found 436.0372. Anal. Calcdfor C17H20BrNO6: C, 49.29; H, 4.87; N, 3.38; Br, 19.29. Found: C, 49.59; H, 5.00; N, 3.47;Br, 18.75.
 

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