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Chemical Structure| 35711-47-8 Chemical Structure| 35711-47-8

Structure of 35711-47-8

Chemical Structure| 35711-47-8

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Product Details of [ 35711-47-8 ]

CAS No. :35711-47-8
Formula : C12H12N2O
M.W : 200.24
SMILES Code : O=CC1=C(C)N(C2=CC=CN=C2)C(C)=C1
MDL No. :MFCD03031163
InChI Key :PELMABXCQSKCNO-UHFFFAOYSA-N
Pubchem ID :799621

Safety of [ 35711-47-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H319
Precautionary Statements:P305+P351+P338

Application In Synthesis of [ 35711-47-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 35711-47-8 ]

[ 35711-47-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 5676-56-2 ]
  • [ 35711-47-8 ]
  • (E)-5-bromo-2-(2-(2,5-dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl)vinyl)benzo[d]oxazole [ No CAS ]
YieldReaction ConditionsOperation in experiment
38% With potassium tert-butylate; In tetrahydrofuran; tert-butyl alcohol; at 0 - 20℃; for 12h; [0518] Compound 73a: To a stirred solution of Comp-79b (0.2 g, 1.00 mmol) and Comp-8e (0.2 g, 1.10 mmol) in THF:f-BuOH (5 mL 4: 1) was added i-BuOK (0.3 g, 3.00 mmol) at 0 C.and the reaction mixture was stirred at RT for 12 h. Progress of the reaction was (0923) monitored by TLC and LCMS. After completion, the reaction mixture was concentrated under reduced pressure and the crude obtained was purified by column chromatography (0924) (silica, 230-400 mesh, 40-50% EtOAc in hexane) to afford (E)-5-bromo-2-(2-(2,5-dimethyl- l-(pyridin-3-yl)-lH-pyrrol-3-yl)vinyl)benzo[i |oxazole (73a; 0.15 g, 38%) as a yellow solid. (0925) [0519] MS (ESI) m/e [Mu+Eta] 7Rt/%: 394.10/2.34/85.37%
  • 2
  • [ 5676-56-2 ]
  • [ 35711-47-8 ]
  • (E)-5-(4,4-difluoropiperidin-1-yl)-2-(2-(2,5-dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl)vinyl)benzo[d]oxazole [ No CAS ]
 

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Related Functional Groups of
[ 35711-47-8 ]

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Related Parent Nucleus of
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Pyridines

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