Alternatived Products of [ 35929-79-4 ]
Product Details of [ 35929-79-4 ]
CAS No. : | 35929-79-4 |
MDL No. : | MFCD00087104 |
Formula : |
C19H22ClNO4
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
363.84
|
Pubchem ID : | - |
Synonyms : |
|
Application In Synthesis of [ 35929-79-4 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Upstream synthesis route of [ 35929-79-4 ]
- Downstream synthetic route of [ 35929-79-4 ]
- 1
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[ 104-88-1 ]
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[ 539-88-8 ]
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[ 35929-79-4 ]
Yield | Reaction Conditions | Operation in experiment |
88% |
With ammonium acetate In neat (no solvent) at 55℃; for 3h; Green chemistry; |
General Procedure for the Synthesis ofPolyhydroquinolines and Dihydropyridines
General procedure: Polyhydroquinolines and DihydropyridinesA mixture of aldehyde (1 mmol), β-dicarbonyl compound (1or 2 mmol), NH4OAc (2.5 mmol), dimedone (1 mmol, whenused), and SBA-15/NHSO3H (5 mol%) was stirred at 55 °C.After complete disappearance of starting material asindicated by TLC, the resulting mixture was diluted with hotEtOAc (10 mL) and filtered. The catalyst was completelyrecovered from the residue |
- 2
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[ 35929-79-4 ]
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[ 105-45-3 ]
-
[ 73257-49-5 ]
Yield | Reaction Conditions | Operation in experiment |
91% |
With ammonium hydroxide; In ethanol; at 110℃;Flow reactor; |
General procedure: Diethyl 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate (4a). EtOH solution (3 mL) ofbenzaldehyde (0.67 M) mixed with ethyl acetoacetate (1.34 M) and the 25% aqueous NH3 (3 mL) wererespectively transferred into gas-tight syringe 1 and syringe 2. The syringes were placed in a LongerLSP02-1B syringe pump which was set to deliver the reactants into the mixer at identical flow rate of 6.7muL/min. The reaction mixture was then allowed to flow through a stainless steel tube reactor which wasdipped in a 110 C oil bath. The output mixture was collected in a cooled sample vial. After reactioncompletion, rinsed the reactor with ethanol to collect all of the reactant solution and then concentratedunder vacuum. The residue was subjected to silica gel column chromatography with Pet-EA (5:1) aseluent to give 4a (612mg, 93% yield). |