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Chemical Structure| 36178-60-6 Chemical Structure| 36178-60-6

Structure of 36178-60-6

Chemical Structure| 36178-60-6

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Product Details of [ 36178-60-6 ]

CAS No. :36178-60-6
Formula : C10H13N
M.W : 147.22
SMILES Code : C1(NCC2CC2)=CC=CC=C1
MDL No. :MFCD03211294

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Application In Synthesis of [ 36178-60-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 36178-60-6 ]

[ 36178-60-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 129112-65-8 ]
  • [ 36178-60-6 ]
  • 2-chloro-N-(cyclopropylmethyl)-7-nitro-N-phenylquinazolin-4-amine [ No CAS ]
YieldReaction ConditionsOperation in experiment
With sodium hydride; In N,N-dimethyl-formamide; at 20℃; for 1.0h; To a solution of <strong>[129112-65-8]2,4-dichloro-7-nitroquinazoline</strong> (250 mg, 1.024 mmol) in DMF (5.1 mL) were added N-(cyclopropylmethyl)aniline (151 mg, 1.024 mmol) and sodium hydride (24.58 mg, 1.024 mmol), and the mixture was stirred for 1 h at RT. The reaction mixture was diluted with AcOEt and washed successively with water and brine. The organic layer was concentrated in vacuo. The residue was used for the next step without further purification. LCMS(m/z) 355.18 [M+H]+.
 

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