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Chemical Structure| 363179-59-3 Chemical Structure| 363179-59-3

Structure of 363179-59-3

Chemical Structure| 363179-59-3

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Product Citations

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El-Abadelaha, Mustafa ; Al-Soudb, Yaseen ; Zahraa, Jalal ; Khanfar, Monther ; Geelen, Lasse ; Kalscheuer, Rainer , et al.

Abstract: A new thieno[2,3-b][1,4]dithiine-1,1-dioxide was prepared via intramolecular cycloaddition reaction between methyl β-sulfonyl ester of thiophene and carbon disulfide (CS2) or ethoxycabonyl isothiocyanate. A new compound methyl 2-((2,5-dichlorothiophen-3-yl)sulfonyl)acetate as methyl β-sulfonyl ester was prepared via interaction between methyl 2-bromoacetate and sodium 2,5-dichlorothiophene-3-sulfinate, which utilized in the cycloaddition reactions. Compounds 17 and 19b were tested for their activity against Staphylococcus aureus and Escherichia coli. Additionally, 17 and 19b were assessed for their activity against Mycobacterium tuberculosis strain mc26230. The tested compounds have shown insignificant activities toward the tested bacteria (minimal inhibitory concentration > 100 μM).

Keywords: Synthesis ; Thieno[2,3-b][1,4] dithiine-1,1-dioxide ; activity

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Product Details of [ 363179-59-3 ]

CAS No. :363179-59-3
Formula : C4HCl2NaO2S2
M.W : 239.08
SMILES Code : O=S(C1=C(Cl)SC(Cl)=C1)[O-].[Na+]
MDL No. :MFCD03093826
InChI Key :VUYAANWWKDAVGG-UHFFFAOYSA-M
Pubchem ID :23683335

Safety of [ 363179-59-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
 

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