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Structure of 36556-48-6

Chemical Structure| 36556-48-6

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Product Details of [ 36556-48-6 ]

CAS No. :36556-48-6
Formula : C6H4ClF2N
M.W : 163.55
SMILES Code : NC1=CC=C(F)C(F)=C1Cl
MDL No. :MFCD11044823
InChI Key :UKKFELITTUIEND-UHFFFAOYSA-N
Pubchem ID :53255483

Safety of [ 36556-48-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 36556-48-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 36556-48-6 ]

[ 36556-48-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 36556-48-6 ]
  • [ 2613-34-5 ]
  • [ 367-25-9 ]
YieldReaction ConditionsOperation in experiment
99% With sodium hydroxide;palladium; In hydrogenchloride; methanol; water; Example 7 88 ml of methanol, 44 ml of water, 0.2 g of palladium-on-charcoal containing 10% Pd and 0.04 mol of <strong>[2613-34-5]3-chloro-2,4-difluoroaniline</strong> are charged to the same reactor as that of Example 6. A hydrogen pressure is introduced in the reactor, which is heated to 90 C. The hydrogen pressure is kept constant at 1.9*106 Pa absolute at 90 C. During the reaction, sodium hydroxide is added in proportion as hydrochloric acid is given off until an amount is reached which is comparable with that used for a corresponding amount of chlorodifluoroaniline in Example 6. After a period of 3 hours, the degree of conversion of the <strong>[2613-34-5]3-chloro-2,4-difluoroaniline</strong> is 100% and the 2,4-difluoroaniline yield is 99%. The remainder of the conversion product (1%) is composed of 4-fluoroaniline and of traces of aniline.
 

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