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Chemical Structure| 37846-06-3 Chemical Structure| 37846-06-3

Structure of 37846-06-3

Chemical Structure| 37846-06-3

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Product Details of [ 37846-06-3 ]

CAS No. :37846-06-3
Formula : C9H13N
M.W : 135.21
SMILES Code : CNC1=CC=C(CC)C=C1

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Application In Synthesis of [ 37846-06-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 37846-06-3 ]

[ 37846-06-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 18442-22-3 ]
  • [ 37846-06-3 ]
  • C18H19NO2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
80% With palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In toluene; at 100℃; for 12h;Inert atmosphere; Example 87B: To a stirred solution of 4-ethyl-N-methylaniline ([37846-06-3], 0.5 g, 3.70 mmol) and <strong>[18442-22-3]7-bromochroman-4-one</strong> ([18442-22-3], 1.0 g, 4.44 mmol) in toluene (10 mL) was added Cs2C03 (2.4 g, 7.40 mmol), BINAP (184 mg, 0.29 mmol) and Pd(OAc)2 (66 mg, 0.29 mmol). The reaction was stirred at 100 C for 12 h under inert atmosphere. The mixture was partitioned between water and EtOAc. The organic layer was concentrated and purified by silica- gel column chromatography [gradient elution with 10% EtOAc in Hexane] to afford the target compound (800 mg, 80.0%) as a brown solid. LCMS MH+ calculated, 282.1, found, 282.2.
 

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