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Chemical Structure| 37878-67-4 Chemical Structure| 37878-67-4

Structure of 37878-67-4

Chemical Structure| 37878-67-4

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Product Details of [ 37878-67-4 ]

CAS No. :37878-67-4
Formula : C10H15N3O
M.W : 193.25
SMILES Code : NC1=CC=C(N2CCOCC2)C(N)=C1
MDL No. :MFCD01918901

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Application In Synthesis of [ 37878-67-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 37878-67-4 ]

[ 37878-67-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 110-91-8 ]
  • [ 5131-60-2 ]
  • [ 37878-67-4 ]
YieldReaction ConditionsOperation in experiment
72% With potassium hydroxide; at 60℃; for 0.5h;Green chemistry;Catalytic behavior; General procedure: In a round-bottomed flask equipped with mechanical stirrer,aryl halide (1 mmol), amine (1.2 mmol), catalyst (5 mg) and KOH(2 mmol) were stirred in ethanol (5 ml) under air atmosphere at 60C for 0.5 h. The progress of the reaction was monitored by TLC and GC. After completion of the reaction, CH2Cl2 (15 ml) was added and the catalyst was separated using an external magnet. The organic layer was washed with water (3 x 10 ml) and dried over anhydrous MgSO4. The product was isolated by column chromatography (nhexaneeethylacetate, 5:1) to afford the corresponding products.The products were characterized by their physical properties,melting points, and FT-IR, 1H NMR and 13C NMR [69-71].
 

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