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Chemical Structure| 3826-47-9 Chemical Structure| 3826-47-9

Structure of 3826-47-9

Chemical Structure| 3826-47-9

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Product Details of [ 3826-47-9 ]

CAS No. :3826-47-9
Formula : C14H11FO
M.W : 214.24
SMILES Code : FC1=CC=CC=C1CC(C2=CC=CC=C2)=O
MDL No. :MFCD02260682

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Application In Synthesis of [ 3826-47-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 3826-47-9 ]

[ 3826-47-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 178686-24-3 ]
  • [ 3826-47-9 ]
  • [ 57-13-6 ]
  • [ 1283117-10-1 ]
YieldReaction ConditionsOperation in experiment
23.8% With hydrogenchloride; In ethanol; water; for 48.0h;Reflux; 00158] To a solution of 2-(2-fluorophenyl)-l-phenylethanone (200 mg, 0.93 mmol),<strong>[178686-24-3]3-ethoxy-4-hydroxy-5-nitrobenzaldehyde</strong> (196 mg, 0.93 mmol) and urea (846 mg, 1.4 mmol) in 20 mL of ethanol was added 0.2 mL of concentrated HCl, the mixture was stirred at reflux for 2 days. After the solvent was removed under reduced pressure, the residue was purified by reverse-phase preparatory HPLC (26-53% acetonitrile + 0.1% trifluoroacetic acid in water + 0.1% trifluoroacetic acid, over 15 min. ) to give Compound 13 (100 mg, yield 23.8%). 1H NMR (DMSO- 6 400 MHz): delta 10.26 (s, 1H), 8.81 (s, 1H), 7.53 (s, 1H), 7.35 (d, J = 1.6 Hz, 1H), 7.22-6.87 (m, 7H), 5.22 (s, 1H), 4.00 (m, 2H), 1.31 (t, J = 12 Hz, 3H); MS (ESI): m/z 450.2 [M+l]+.
  • 2
  • [ 326-62-5 ]
  • potassium phenyltrifluoborate [ No CAS ]
  • [ 3826-47-9 ]
 

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