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Chemical Structure| 388072-09-1 Chemical Structure| 388072-09-1

Structure of 388072-09-1

Chemical Structure| 388072-09-1

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Product Details of [ 388072-09-1 ]

CAS No. :388072-09-1
Formula : C6H9NO
M.W : 111.14
SMILES Code : NCC1=C(C)C=CO1
MDL No. :MFCD09811371

Safety of [ 388072-09-1 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H226-H302-H312-H332-H335-H314
Precautionary Statements:P210-P240-P241-P242-P243-P260-P264-P270-P271-P280-P301+P330+P331-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378-P403+P233-P403+P235-P405-P501
Class:8(3)
UN#:2734
Packing Group:

Application In Synthesis of [ 388072-09-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 388072-09-1 ]

[ 388072-09-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 105763-77-7 ]
  • [ 388072-09-1 ]
  • 2-chloro-6-methoxy-N-((3-methylfuran-2-yl)methyl)quinazolin-4-amine [ No CAS ]
YieldReaction ConditionsOperation in experiment
74% With triethylamine; In tetrahydrofuran; for 0.5h;Reflux; General procedure: To a mixture of 2,4-dichloro-quinazoline 5a (0.459 g,2.31 mmol) in THF (7.7 mL), trimethylamine (Et3N) (0.39 mL,2.77 mmol) and furfuryl amine (0.24 mL, 2.77 mmol) was addeddrop-wise. The reaction was heated to reflux for 30 min. After coolingto rt, the reaction residue was extracted three times with CH2-Cl2 (30 mL), dried over MgSO4, concentrated under reducedpressure, and purified by column chromatography (EtOAc/n-Hex = 2:5) on silica gel to get the title product 6a in 92% yield(552 mg).
 

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