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Chemical Structure| 39221-60-8 Chemical Structure| 39221-60-8

Structure of 39221-60-8

Chemical Structure| 39221-60-8

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Product Details of [ 39221-60-8 ]

CAS No. :39221-60-8
Formula : C6H12BrNO
M.W : 194.07
SMILES Code : CCC(Br)C(N(C)C)=O
MDL No. :MFCD17235599

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Application In Synthesis of [ 39221-60-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 39221-60-8 ]

[ 39221-60-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 39221-60-8 ]
  • [ 13808-62-3 ]
  • [ 124-41-4 ]
  • [ 59843-85-5 ]
  • [ 59843-84-4 ]
YieldReaction ConditionsOperation in experiment
In tetrahydrofuran; Alternate Synthesis for alpha-ethyl-N,N,4-trimethyl-3-phenylpyrazole-1-acetamide Sodium methoxide powder (216 g., 4.0 mole) was added over 10 minutes at a stirred solution of <strong>[13808-62-3]4-methyl-3-phenylpyrazole</strong> (632 g., 4.0 mole) in tetrahydrofuran (1.0 liter) at 10 C. 2-Bromo-N,N-dimethylbutyramide (911 g., 4.7 mole) was added dropwise over 30 minutes while maintaining the temperature of the reaction solution below 30 C. by external cooling. The solution was stirred for an additional 30 minutes at room temperature, and the THF was then removed under reduced pressure. The residual oil was partitioned between chloroform and water. The chloroform layer was evaporated and the residual oil was recrystallized from benzene:Skellysolve B to give 772 g. of alpha-ethyl-N,N,4-trimethyl-3-phenylpyrazole-1-acetamide, m.p. 85.5-87.5 C. Evaporation of the crystallization mother liquors gave 365 g. of oil containing additional product.
 

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