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Chemical Structure| 41458-73-5 Chemical Structure| 41458-73-5

Structure of 41458-73-5

Chemical Structure| 41458-73-5

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Product Details of [ 41458-73-5 ]

CAS No. :41458-73-5
Formula : C7H14N2O2
M.W : 158.20
SMILES Code : CNCC(N1CCOCC1)=O
MDL No. :MFCD06358653

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Application In Synthesis of [ 41458-73-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 41458-73-5 ]

[ 41458-73-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 902586-59-8 ]
  • [ 41458-73-5 ]
  • 9-chloro-N-methyl-N-(2-morpholino-2-oxo-ethyl)-5,6,7,8-tetrahydroacridine-3-carboxamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
General procedure: 9-Chloro-5,6,7,8-tetrahydroacridine-3-carboxylic acid (100 mg, 0.38 mmol) was dissolved in 2 ml of N,N-dimethylformamide (DMF) and charged with 1-[bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxide hexafluorophosphate (HATU) (144 mg, 0.38 mmol). After stirring at room temperature for 30 min, the mixture was then charged with 3-((5-chloro-2,4-dimethoxyphenyl)amino)propanenitrile (91 mg, 0.38 mmol). The resulting solution was stirred at 110 C for 1 h, dilutedwith of 50 ml of ethyl acetate, and then extracted with ethyl acetate (2 × 100 ml).The combined organic layers were washed with brine (3 × 200 ml), dried over anhydrous sodium sulfate, and concentrated under vacuum. The residue was purified on a silica gel column eluting with ethyl acetate/petroleum ether (1:100 to 1:10) to afford the title compound (110 mg, 0.30 mmol, 78% yield) of the title compound.
 

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