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Type HazMat fee for 500 gram (Estimated)
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Chemical Structure| 41739-23-5 Chemical Structure| 41739-23-5

Structure of 41739-23-5

Chemical Structure| 41739-23-5

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Product Details of [ 41739-23-5 ]

CAS No. :41739-23-5
Formula : C5H6F2O2
M.W : 136.10
SMILES Code : CC(=O)CC(=O)C(F)F
MDL No. :MFCD02254117

Safety of [ 41739-23-5 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H225-H315-H319-H335
Precautionary Statements:P210-P261-P305+P351+P338
Class:3
UN#:1993
Packing Group:

Application In Synthesis of [ 41739-23-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 41739-23-5 ]

[ 41739-23-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 41739-23-5 ]
  • [ 108290-86-4 ]
  • ethyl 4-(difluoromethyl)-2-methylpyrrolo[1,2-a]pyrimidine-8-carboxylate [ No CAS ]
  • ethyl 2-(difluoromethyl)-4-methylpyrrolo[1,2-a]pyrimidine-8-carboxylate [ No CAS ]
YieldReaction ConditionsOperation in experiment
18%; 33% With acetic acid; at 110℃; for 0.666667h; [00254] To a mixture of ethyl 2-amino-lH-pyrrole-3-carboxylate (616 mg, 4 mmol) in AcOH (10 mL) at 110 C was added 1 , 1 -difluoropentane-2,4-dione (653 mg, 4.8 mmol). The solution was stirred at 1 10 C for 40 minutes, cooled to room temperature and concentrated in vacuo. The resulting residue was purified by silica gel column chromatography (EA:PE = 3:7) to give ethyl 2-(difluoromethyl)-4-methylpyrrolo[l,2-a]pyrimidine-8-carboxylate (340 mg, 33%) as a yellow solid and ethyl 4-(difluoromethyl)-2-methylpyrrolo[l,2-a]pyrimidine-8- carboxylate (180 mg, 18%) as a brown oil.
 

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