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Chemical Structure| 423-62-1 Chemical Structure| 423-62-1

Structure of Henicosafluoro-10-iododecane
CAS No.: 423-62-1

Chemical Structure| 423-62-1

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Product Details of [ 423-62-1 ]

CAS No. :423-62-1
Formula : C10F21I
M.W : 645.98
SMILES Code : IC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
MDL No. :MFCD00001065
InChI Key :UDWBMXSQHOHKOI-UHFFFAOYSA-N
Pubchem ID :67920

Safety of [ 423-62-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 423-62-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 423-62-1 ]

[ 423-62-1 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 423-62-1 ]
  • [ 13406-29-6 ]
  • (perfluorodecyl)bis[4-(trifluoromethyl)phenyl]phosphine [ No CAS ]
YieldReaction ConditionsOperation in experiment
61%Spectr. at 15 - 25℃; for 30h;Irradiation; Sealed tube; Inert atmosphere; General procedure: PAr 3 (0.1 mmol), perfluoroalkyl iodide (Rf-I, 0.2 mmol), and benzotrifluoride (BTF) (1 mL) were placed in a sealed Pyrex® glass NMR tube under an argon atmosphere . The mixture was stirred for 30 seconds and then the mixture was irradiated with a xenon lamp (500 W) at room temperature (eg 15 ° C. to 25 ° C.) for 30 hours.The formation of RfPAr 2 was confirmed by 19 F NMR analysis. The crude mixture was poured into a 30 mL Schlenk tube and evaporated. MeOH (2 mL) (Wako Pure Chemical Industries, special grade, used after distillation) was added to the flask and the product was extracted with FC-72 (3 mL × 5) (3Me Japan Co., Ltd.).The product obtained was sufficiently pure without further purification. The spectrum and analytical data of 1a have already been shown in the literature (Kawaguchi et al., Angew. Chem. Int. Ed. 2013, 52, 1748-1752.). The applicable range of the substrate is shown in Table 1
  • 2
  • [ 423-62-1 ]
  • [ 15754-51-5 ]
  • di(p-methoxylphenyl)(2,4,6-trimethylbenzoyl)phosphine oxide [ No CAS ]
  • (perfluorodecyl)bis(4-(methoxy)phenyl)phosphine [ No CAS ]
YieldReaction ConditionsOperation in experiment
63% at 15 - 25℃; for 1.5h;Irradiation; Inert atmosphere; Sealed tube; General procedure: TMDPO (0.2 mmol), perfluoroalkyl iodide (nC 10 F 21 I, 0.1 mmol), Cy 2 P (O) H (0.2 mmol) and benzotrifluoride (BTF) (0.6 mL) were placed in a sealed Pyrex Registered trademark) glass tube. The mixture was stirred for 30 seconds and then the mixture was irradiated with a xenon lamp (500 W) at room temperature (eg 15 C. to 25 C.) for 1.5 hours. The formation of Compound 11 was confirmed by 19 F NMR analysis. The crude mixture was poured into a 30 mL Schlenk tube and evaporated. MeOH (2 mL) was added to the Schlenk tube and the product was extracted with FC-72 (3 mL × 5). The product obtained (fluorine-containing solvent layer) was sufficiently pure without further purification
63% With (2,4,6-trimethylbenzoyl)diphenylphosphine oxide; at 15 - 25℃; for 1.5h;Irradiation; Sealed tube; TMDPO (0.2 mmol), perfluoroalkyl iodide (nC 10 F 21 I, 0.1 mmol), Cy 2 P (O) H (0.2 mmol) and benzotrifluoride (BTF) (0.6 mL) were placed in a sealed Pyrex Registered trademark) glass tube. The mixture was stirred for 30 seconds,The mixture was then irradiated with a xenon lamp (500 W) at room temperature (eg 15 C. to 25 C.) for 1.5 h. The formation of Compound 11 was confirmed by 19 F NMR analysis. The crude mixture was poured into a 30 mL Schlenk tube,Evaporated. MeOH (2 mL) was added to the Schlenk tube and the product was extracted with FC-72 (3 mL × 5). The product obtained (fluorine-containing solvent layer) was sufficiently pure without further purification. Using a derivative of TMDPO as a raw material, a perfluorophosphine compound was synthesized using the same method as in Example 1-5. The results are shown in Table 4
 

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