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Chemical Structure| 43115-40-8 Chemical Structure| 43115-40-8

Structure of 43115-40-8

Chemical Structure| 43115-40-8

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Product Details of [ 43115-40-8 ]

CAS No. :43115-40-8
Formula : C8H11NO3S
M.W : 201.24
SMILES Code : OC1=CC=C(S(=O)(CC)=O)C=C1N
MDL No. :MFCD00035895
InChI Key :UPJVUFCLBYQKFH-UHFFFAOYSA-N
Pubchem ID :643218

Safety of [ 43115-40-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 43115-40-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 43115-40-8 ]

[ 43115-40-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 10241-97-1 ]
  • [ 43115-40-8 ]
  • [ 783370-02-5 ]
YieldReaction ConditionsOperation in experiment
15% With triethanolamine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; In N,N-dimethyl-formamide; EXAMPLE 48 5-Methyl-1H-indole-2-carboxylic acid-(5-ethanesulfonyl-2-hydroxy-phenyl)-amide TEA (0.28 mL, 2.0 mmole) was added to a solution of <strong>[10241-97-1]5-methyl-1H-indole-2-carboxylic acid</strong> (175 mg, 1.0 mmole), 2-amino-4-ethanesulfonyl-phenol (201 mg, 1.0 mmole), and BOP (442 mg, 1.0 mmole) in DMF (2.0 mL). The reaction mixture was shaken at room temperature overnight and then diluted with 1N hydrochloric acid (20 mL). The resulting precipitate was filtered off and washed with water. The residue was triturated with EtOAc (40 mL), the solvent was dried over magnesium sulfate, filtered, and reduced in volume while slowly adding hexanes until crystallization began. The crystalline product was filtered off and air-dried to afford the title compound as a brown powder (55 mg, 15percent yield). AP-/MS=359; AP-/MS=357.
  • 2
  • [ 6624-49-3 ]
  • [ 43115-40-8 ]
  • [ 1118623-67-8 ]
 

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