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Chemical Structure| 439116-15-1 Chemical Structure| 439116-15-1

Structure of 439116-15-1

Chemical Structure| 439116-15-1

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Product Details of [ 439116-15-1 ]

CAS No. :439116-15-1
Formula : C13H19ClN2O2
M.W : 270.76
SMILES Code : O=C(OC(C)(C)C)NCC1=CC=C(Cl)C=C1CN

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Application In Synthesis of [ 439116-15-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 439116-15-1 ]

[ 439116-15-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 38675-10-4 ]
  • [ 439116-15-1 ]
  • N-(tert-butoxyacetyl)-D-phenylalanyl-N-(2-[(tert-butoxycarbonyl)amino]methyl}-5-chlorobenzyl)-L-prolinamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
With 1,2-dichloro-ethane; In N-methyl-acetamide; Step A N-(tert-butoxyacetyl)-D-phenylalanyl-N-(2-[(tert-butoxycarbonyl)amino]methyl}-5-chlorobenzyl)-L-prolinamide To a solution of tert-Butyl 2-(aminomethyl)-4-chlorobenzylcarbamate (0.14 mmol, 37 mg), EDC (0.21 mmol, 40 mg), and <strong>[38675-10-4]Boc-D-Phe-Pro-OH</strong> (0.14 mmol, 50 mg), in 0.5 mL dimethylformamide, was added HOAT (0.15 mmol, 21 mg). The solution was stirred overnight and purified by prep HPLC to give N-(tert-Butoxyacetyl)-D-phenylalanyl-N-(2-{(tert-butoxycarbonyl)amino]methyl}-5-chlorobenzyl)-L-prolinamide. Mass Spec ES (M+1)=615.2.
 

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