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Chemical Structure| 443956-14-7 Chemical Structure| 443956-14-7

Structure of 443956-14-7

Chemical Structure| 443956-14-7

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Product Details of [ 443956-14-7 ]

CAS No. :443956-14-7
Formula : C8H6N2O3S
M.W : 210.21
SMILES Code : O=C(C1=CC=C(C(N2)=N1)SCC2=O)O
MDL No. :MFCD18260622

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Application In Synthesis of [ 443956-14-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 443956-14-7 ]

[ 443956-14-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 118753-66-5 ]
  • [ 443956-14-7 ]
  • [ 877177-43-0 ]
YieldReaction ConditionsOperation in experiment
78% With benzotriazol-1-ol; 1,2-dichloro-ethane; In dichloromethane; N,N-dimethyl-formamide; for 12.0h; To a solution of 1 ,1-dimethylethyl 4-amino-1 -piperazinecarboxylate (270 mg, 1.34 mmol) in DCM-DMF (4:1 , 15 ml_) were added 3-oxo-3,4-dihydro-2H-pyrido[3,2- i?][1 ,4]thiazine-6-carboxylic acid (283 mg, 1.34 mmol), EDC (250 mg, 1.61 mmol) and HOBT (217 mg, 1.61 mmol). After 12h, the solution was concentrated and the residue purified via column chromatography (silica, 1% MeOH in DCM (1% NH4OH)) yielding the title compound as a yellow foam (412 mg, 78 %): LCMS (ES) m/e 394 (M+H)+.
 

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