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Chemical Structure| 4526-56-1 Chemical Structure| 4526-56-1

Structure of 6-Chloro-2,4-dibromophenol
CAS No.: 4526-56-1

Chemical Structure| 4526-56-1

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Product Details of [ 4526-56-1 ]

CAS No. :4526-56-1
Formula : C6H3Br2ClO
M.W : 286.35
SMILES Code : OC1=C(Cl)C=C(Br)C=C1Br
MDL No. :MFCD00029692
InChI Key :MQSIWVCWTVYFDP-UHFFFAOYSA-N
Pubchem ID :20621

Safety of [ 4526-56-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 4526-56-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 4526-56-1 ]

[ 4526-56-1 ] Synthesis Path-Upstream   1~4

  • 1
  • [ 95-57-8 ]
  • [ 3964-56-5 ]
  • [ 2040-88-2 ]
  • [ 4526-56-1 ]
YieldReaction ConditionsOperation in experiment
75% With N-Bromosuccinimide; thiourea In acetonitrile at 20℃; for 2 h; General procedure: Reaction conditions: Thiourea (5.1 molpercent, 2 mg, 0.026 mmol) was added to an acetonitrile solution (10 mL) containing NBS (1.15 equiv, 104.4 mg, 0.587 mmol). Anisole (56.3 mg, 0.51 mmol) was added immediately to the resulting stirred solution and allowed to stir at room temperature for 10 min. The reaction was quenched by the addition of 10percent aqueous solution of Na2S2O3 (10 mL) and extracted with ethyl acetate (70 mL). The organic solution was then washed with additional 10percent Na2S2O3 (2 * 10 mL), followed by deionized water (3 * 15 mL) and brine (2 * 10 mL). The organic solution was then dried over anhydrous Na2SO4 and the solvent was evaporated in vacuo. The major product of each reaction was isolated by centrifugal thin-layer chromatography using a 2 mm thick silica gel 60GF254 coated plate (5percent CH2Cl2/hexanes). The products reported herein are known compounds and were characterised by GC-MS, IR, 1H and 13C NMR. Their spectroscopic data are in agreement with those reported in the literature.
References: [1] Tetrahedron, 2017, vol. 73, # 46, p. 6564 - 6572.
[2] Dalton Transactions, 2013, vol. 42, # 33, p. 11926 - 11940.
[3] Journal of Organic Chemistry, 1997, vol. 62, p. 4504 - 4506.
[4] Journal of Organic Chemistry, 1997, vol. 62, p. 4504 - 4506.
[5] Tetrahedron, 2007, vol. 63, # 23, p. 4959 - 4967.
[6] Tetrahedron, 2007, vol. 63, # 23, p. 4959 - 4967.
[7] Tetrahedron, 2010, vol. 66, # 34, p. 6928 - 6935.
  • 2
  • [ 4526-56-1 ]
  • [ 95-57-8 ]
  • [ 2040-88-2 ]
References: [1] European Journal of Organic Chemistry, 1999, # 11, p. 2845 - 2851.
[2] European Journal of Organic Chemistry, 1999, # 11, p. 2845 - 2851.
  • 3
  • [ 95-57-8 ]
  • [ 2040-88-2 ]
  • [ 4526-56-1 ]
References: [1] Bulletin of the Chemical Society of Japan, 1993, vol. 66, # 5, p. 1576 - 1579.
  • 4
  • [ 4526-56-1 ]
  • [ 2040-88-2 ]
References: [1] Journal of Organic Chemistry, 1977, vol. 42, # 5, p. 835 - 838.
 

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