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Chemical Structure| 465514-33-4 Chemical Structure| 465514-33-4

Structure of 465514-33-4

Chemical Structure| 465514-33-4

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Product Details of [ 465514-33-4 ]

CAS No. :465514-33-4
Formula : C11H15NO2
M.W : 193.24
SMILES Code : C1=C(C(=CC=C1)N2CCOCC2)CO
MDL No. :MFCD03086181
InChI Key :MYGVYNRBQSAMIF-UHFFFAOYSA-N
Pubchem ID :2776562

Safety of [ 465514-33-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 465514-33-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 465514-33-4 ]

[ 465514-33-4 ] Synthesis Path-Downstream   1~18

  • 1
  • [ 465514-33-4 ]
  • [ 110405-99-7 ]
  • 2
  • [ 223560-37-0 ]
  • [ 465514-33-4 ]
  • 3
  • [ 58028-76-5 ]
  • [ 465514-33-4 ]
YieldReaction ConditionsOperation in experiment
Reference Example 51 (2-Morpholin-4-ylphenyl)methanol 2-Fluorobenzaldehyde (1.0 g, 8.1 mmol) was dissolved in DMF (20 mL), morpholine (2.0 mL) and potassium carbonate (1.1 g, 8.1 mmol) were added thereto, and then the mixture was stirred at 80C for 2 days. To the reaction solution was added water, and the reaction mixture was extracted with ethyl acetate. The extract was dried, and then concentrated under reduced pressure. The residue was purified with silica gel column chromatography (hexane/ethyl acetate = 98: 2 to 60: 40) to give an oily matter. The resulting oily matter was dissolved in methanol (20 mL), sodium borohydride (613 mg, 16.2 mmol) was added thereto, and the mixture was stirred at room temperature for 3 hours. To the reaction solution was added water, and the reaction mixture was extracted with ethyl acetate. The extract was dried, and then concentrated under reduced pressure to give the title compound (474 mg, yield 30%).
  • 4
  • [ 501371-91-1 ]
  • [ 465514-33-4 ]
  • 1-cyclohexyl-2-[2-fluoro-4-(2-morpholin-4-ylbenzyloxy)phenyl]-1H-benzimidazole-5-carboxylic acid methyl ester [ No CAS ]
  • 5
  • [ 465514-33-4 ]
  • 1-cyclohexyl-2-[2-fluoro-4-(2-morpholin-4-ylbenzyloxy)phenyl]-1H-benzimidazole-5-carboxylic acid [ No CAS ]
  • 6
  • [ 394-35-4 ]
  • [ 465514-33-4 ]
  • 7
  • [ 465514-33-4 ]
  • [ 117323-28-1 ]
  • 8
  • [ 465514-33-4 ]
  • 2-[(2-morpholino)benzylsulfinyl]-1-(2-pyridyl)imidazole [ No CAS ]
  • 9
  • [ 465514-33-4 ]
  • [ 117323-22-5 ]
  • 10
  • [ 465514-33-4 ]
  • 4-{2-[1-(3-Methyl-pyridin-2-yl)-1H-imidazole-2-sulfinylmethyl]-phenyl}-morpholine [ No CAS ]
  • 11
  • [ 465514-33-4 ]
  • 4-[2-(1-Pyridin-2-yl-1H-imidazole-2-sulfonylmethyl)-phenyl]-morpholine [ No CAS ]
  • 12
  • [ 465514-33-4 ]
  • [ 117323-81-6 ]
  • 13
  • [ 465514-33-4 ]
  • [ 117323-27-0 ]
  • 14
  • [ 465514-33-4 ]
  • 4-{2-[1-(3-Methyl-pyridin-2-yl)-1H-imidazole-2-sulfonylmethyl]-phenyl}-morpholine [ No CAS ]
  • 15
  • [ 465514-33-4 ]
  • 2-(2-Morpholin-4-yl-phenylmethanesulfinyl)-1-pyridin-2-yl-1,4,5,6-tetrahydro-cyclopentaimidazole [ No CAS ]
  • 16
  • [ 465514-33-4 ]
  • 4-{2-[1-(3-Methoxy-pyridin-2-yl)-1H-imidazole-2-sulfinylmethyl]-phenyl}-morpholine [ No CAS ]
  • 17
  • [ 465514-33-4 ]
  • 4-{2-[1-(3-Methoxy-pyridin-2-yl)-1H-imidazole-2-sulfonylmethyl]-phenyl}-morpholine [ No CAS ]
  • 18
  • [ 465514-33-4 ]
  • 2-(2-Morpholin-4-yl-phenylmethanesulfonyl)-1-pyridin-2-yl-1,4,5,6-tetrahydro-cyclopentaimidazole [ No CAS ]
 

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