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Chemical Structure| 470484-70-9 Chemical Structure| 470484-70-9

Structure of 470484-70-9

Chemical Structure| 470484-70-9

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Product Details of [ 470484-70-9 ]

CAS No. :470484-70-9
Formula : C8H4BrClN2
M.W : 243.49
SMILES Code : ClC1=NN=CC2=CC(Br)=CC=C12
MDL No. :MFCD09264004
InChI Key :GHENEHYQUQKATD-UHFFFAOYSA-N
Pubchem ID :22030424

Safety of [ 470484-70-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 470484-70-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 470484-70-9 ]

[ 470484-70-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 4138-26-5 ]
  • [ 470484-70-9 ]
  • [ 909186-60-3 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In acetonitrile; at 190℃; for 0.333333h;microwave irradiation; A glass microwave reaction vessel was charged with <strong>[4138-26-5]nipecotamide</strong> (0.17 g, 1.4 mmol), 6-bromo-1-chlorophthalazine (0.110 g, 0.45 mmol), potassium carbonate (0.062g, 0.45 mmol) and 3 mL acetonitrile. The reaction mixture was stirred and heated in a Smith Synthesizer.(R). microwave reactor (Personal Chemistry, Inc., Upssala, Sweden) at 190° C. for 20 min (watts, Powermax feature on, ramp time 1 min). The mixture was purified directly via flash chromatography (silica gel) eluting with 4/1 hexanes/EtOAc to 4/1 hexanes/EtOAc to give (0.15 g) 1-(6-bromophthalazin-1-yl)<strong>[4138-26-5]piperidine-3-carboxamide</strong> as a white solid. Found MS (ES+): 335, 337(M+H)+.
 

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